Cell Physiology and Molecular Biophysics
John C. Fowler
Associate Professor of Physiology
Ph.D. in Medical Sciences, University of New Mexico , Albuquerque, 1982
Cardiovascular-Related Research Competitive Renewal
Table of Contents
- Original Cardiovascular-Related Research Seed grant - 09/01/2005
- Cardiovascular-Related Research Competitive Renewal - 04/17/2006
- Ischemic return of evoked potentials and neuronal damage in energy-deprived rat hippocampal slice.
Titus, Rebin T., Martinez, Gloria M., Omidvar, Kamran and Fowler, John C. - 04/04/2007
- Summary Statement, Application: R21 NS055070-0, PI: Fowler, John C
My general interest is the regulation of neuronal electrophysiological activity at the cellular level. Presently, I am investigating mechanisms responsible for ischemic alteration in neuronal electrical activity in the isolated mammalian hippocampal slice preparation. I have a growing interest in using electrophysiological, pharmacological and biochemical techniques in exploring mechanisms of neurotoxicity.
My current interest is the interactions of the endogenous inhibitory neuromodulator adenosine, the excitatory neurotransmitter glutamate, and neuronal function during metabolic stress. At this time I am specifically interested in the role of adenosine in hypoxia and ischemia-induced depression of neuronal activity in the rat brain in vivo.
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