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Cell Physiology and Molecular Biophysics

Thomas A. Pressley



Pressley, T.A., Graves, J.S. and Krall, A.R. Amiloride-sensitive ammonium and sodium ion transport in the blue crab. Am. J. Physiol. 241:R370-R378, 1981.

Pressley, T.A., and Graves, J.S. Increased amino acid oxidation in the gills of blue crabs acclimated to dilute seawater. J. Exp. Zool. 226:45-51, 1983.

Edelman, I.S., Pressley, T.A. and Hiatt, A. Regulation of mammalian Na,K-ATPase. In: The Sodium Pump, eds. Glynn, I., and Ellory, C. Company of Biologists. Ltd., Cambridge, England, pp. 153-159, 1985.

Pressley, T.A., Haber, R.S., Loeb, J.N., Edelman, I.S. and Ismail-Beigi. F. Stimulation of Na,K-activated adenosine triphosphatase and active transport by low external K+ in a rat liver cell line. J. Gen. Physiol. 87:591-606, 1986.

Pressley, T.A., and Edelman, I.S. Reduced ouabain inhibition of Na,K-activated adenosine triphosphatase in cultured cell recipients of the ouabain-resistance gene. J. Biol. Chem. 261:9779-9786, 1986.

Haber, R.S., Pressley, T.A., Loeb, J.N. and Ismail-Beigi, F. Ionic dependence of active Na,K transport: "clamping" of cellular Na+ with monensin. Am. J. Physiol. 253:F26-F33, 1987.

Ismail-Beigi, F., Pressley, T.A., Haber, R.S., Gick, G.G., Loeb, J.N. and Edelman, I.S. Kinetic analysis of Na,K-activated adenosine triphosphatase induced by low external K+ in a rat liver cell line. J. Biol. Chem. 263:8162-8167, 1988.

Pressley, T.A., Ismail-Beigi, F., Gick, G.G. and Edelman, I.S. Increased abundance of Na+-K+-ATPase mRNAs in response to low external K+. Am. J. Physiol. 255:C252-C260, 1988.

Pressley, T.A. Ion concentration-dependent regulation of Na,K-pump abundance. J. Membr. Biol. 105:187-195, 1988 (Invited Review).

Shoshan-Barmatz, V., Pressley, T.A., Higham, S. and Kraus-Friedmann, N. Characterization of high-affinity ryanodine-binding sites of rat liver endoplasmic reticulum. Differences between liver and skeletal muscle. Biochem. J. 276:41-46, 1991.

Allen, J.C., Medford, R.M., Zhao, X. and Pressley, T.A. Disproportionate alpha- and beta-mRNA sodium pump subunit content in canine vascular smooth muscle. Circ. Res. 69:39-44, 1991.

Medford, R.M., Hyman, R., Ahmad, M., Allen, J.C., Pressley, T.A., Allen, P.D., and Nadal-Ginard, B. Vascular smooth muscle expresses a truncated Na+,K+-ATPase alpha-1 subunit isoform. J. Biol. Chem. 266:18308-18312, 1991.

Allen, J.C., Seidel, C.L., Navran, S.S., Pressley, T.A. and Medford, R.M. Na pump in vascular smooth muscle: Regulation of cell proliferation. In: The Sodium Pump: Recent Developments, eds. De Weer, P., and Kaplan, J.H. Rockefeller University Press, New York, pp. 631-634, 1991.

Pressley, T.A. Ionic regulation of Na+,K+-ATPase expression. Sem. Nephrol. 12:67-71, 1992 (Invited Review).

Pressley, T.A. Phylogenetic conservation of isoform-specific regions within alpha-subunit of Na+-K+-ATPase. Am. J. Physiol. 262:C743-C751, 1992.

Higham, S.C., Melikian, J., Karin, N.J., Ismail-Beigi, F., and Pressley, T.A. Na,K-ATPase expression in C2C12 cells during myogenesis: minimal contribution of alpha2 isoform to Na,K transport. J. Membr. Biol. 131:129-136, 1993.

Scully, R.R., Pressley, T.A., and O'Neil, R.G. A site-directed antibody recognizes a component of the ouabain-binding domain of the alpha1 subunit of rat Na+,K+-ATPase. Biochem. Cell Biol. 71:538-543, 1993.

Medford, R.M., Pressley, T.A., Mercer, R.W., and Allen, J.C. Expression of a truncated subunit of the Na+,K+-ATPase (alpha-1-T) in smooth muscle cells. In: The Sodium Pump: Structure Mechanism, Hormonal Control, and its Role in Disease, eds. Bamberg, E., and Schoner, W. Steinkopff Springer, New York, pp. 192-199, 1994.

Allen, J.C., Pressley, T.A., Odebunmi, T., and Medford, R.M. Tissue specific membrane association of alpha1T, a truncated form of the alpha1 subunit of the Na pump. FEBS Lett. 337:285-288, 1994.

Shanbaky, N.M., and Pressley, T.A. Mammalian alpha1-subunit of Na+-K+-ATPase does not need its amino terminus to maintain cell viability. Am. J. Physiol. 267:C590-C597, 1994.

Pressley, T.A., Higham, S.C., Joson, L.A., and Mercer, D.W. Stimulation of Na+-K+-ATPase by thyrotropin in cultured thyroid follicular cells. Am. J. Physiol. 268:C1252-C1258, 1995.

DuBose, T.D., Jr., Codina, J., Burges, A., and Pressley, T.A. Regulation of H+-K+-ATPase expression in kidney. Am J. Physiol. 269:F500-F507, 1995.

Shanbaky, N.M., and Pressley, T.A. Transfection of Na,K-ATPase alpha-subunit: regulation of enzyme abundance. Biochem. Cell Biol. 73:261-268, 1995.

Pressley, T.A. The Membrane Na+-K+-ATPase in Cells. In: Principles of Medical Biology, Volume 4, Cell Chemistry and Physiology, Part II, eds. Bittar, E.E., and Bittar, N. JAI Press, Greenwich, pp. 243-253, 1996.

Kragenbrink, R., Higham, S.C., Sansom, S.C., and Pressley, T.A. Chronic stimulation of acetylcholine receptors: differential effects on Na,K-ATPase isoforms in a myogenic cell line. Synapse 23:219-223, 1996.

Pressley, T.A., Allen, J.C., Clarke, C.H., Odebunmi, T., and Higham, S.C. Amino terminal processing of the catalytic subunit from Na+-K+-ATPase. Am. J. Physiol., 271:C825-C832, 1996.

Weisbrodt, N.W., Pressley, T.A., Li, Y.-F., Zembowicz, M.J., Higham, S.C., Lodato, R.F., Zembowicz, A., and Moody, F.G. Decreased ileal smooth muscle contractility and increased nitric oxide synthase II expression induced by liposaccharide. Am. J. Physiol. 271:G454-G460, 1996.

Pressley, T.A., and Sabatini, S. Introduction. >Miner. Electrolyte Metab. 22:263, 1996 (Guest Editors' Comments).

Pressley, T.A. Structure and function in the Na,K-pump: ten years of molecular biology. Miner. Electrolyte Metab. 22:264-271, 1996 (Invited Review).

Wang, J., Schwinger, R.H.G., Frank, K., Müller-Ehmsen, J., Martin-Vassalo, P., Pressley, T.A., Xiang, A., Erdmann, E., and McDonough, A.A. Regional expression of sodium pump subunit isoforms and Na+-Ca++ exchanger in the human heart. J. Clin. Invest. 98:1650-1658, 1996.

Codina, J., Pressley, T.A., and DuBose, T.D., Jr. Effect of chronic hypokalemia on H+,K+-ATPase expression in rat colon. Am. J. Physiol. 272:F22-F30, 1997.

Pedemonte, C.H., Pressley, T.A., Lokhandwala, M.F., and Cinelli, A.R. Regulation of Na,K-ATPase transport activity by protein kinase C. J. Membr. Biol. 155:219-227, 1997.

Pedemonte, C.H., Pressley, T.A., Cinelli, A.R., and Lokhandwala, M.F. Stimulation of protein kinase C rapidly reduces intracellular Na+ concentration via activation of the Na+-pump in OK cells. Mol. Pharmacol. 52:88-97, 1997.

Pressley, T.A. A role for uteroglobin in glomerulopathy: knockout mice as a model system. Am. J. Kid. Dis. 30:720-722, 1997 (Journal Club Summary).

Pressley, T.A., and Petrosian, S.A. Posttranslational processing of the catalytic subunit from Na+/K+-ATPase. Ann. N.Y. Acad. Sci. 834:543-544, 1997.

Allen, J.C., Zhao, X., Odebunmi, T., Jemelka, S., Medford, R.M., Pressley, T.A., and Mercer, R.W. Alpha1T can support Na+/K+-ATPase: Na+ pump functions in expression systems. Ann. N.Y. Acad. Sci. 834:457-458, 1997.

Petrosian, S.A., Carr, D.L., Guerrero, G., and Pressley, T.A. Mutagenesis disrupts post-translational processing of the Na,K-ATPase catalytic subunit. Arch. Biochem. Biophys. 357:249-258, 1998.

Pressley, T.A. Molecular biology and the kidney. Am. J. Kid. Dis. 32:1084-1085, 1998 (Editorial).

Chibalin, A.V., Ogimoto, G., Pedemonte, C.H., Pressley, T.A., Katz, A.I. Féraille, E., Berggren, P.-O., and Bertorello, A.M. Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser18 in the rat alpha-subunit and is responsible for the decreased catalytic activity in epithelial cells. J. Biol. Chem. 274:1920-1927, 1999.

LeGrow, A.B., Fielding, D.C., and Pressley, T.A. Stimulation of Na,K-ATPase by hypothyroidism in the thyroid gland. J. Endocrinol. 160:453-460, 1999.

Shao, Y., Pressley, T.A., and Ismail-Beigi, F. Na,K-ATPase mRNA-beta1 expression in rat myocardium: effect of thyroid status. Eur. J. Biochem. 260:1-8, 1999.

Lodato, R.F., Khan, A.R., Zembowicz, M.J., Weisbrodt, N.W., Pressley, T.A., Li, Y.-F., Lodato, J.A., Zembowicz, A., and Moody, F.G. Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccharide. Am. J. Physiol. 276:G1356-G1362, 1999.

Codina, J., Pressley, T.A., and DuBose, T.D., Jr. The colonic H+,K+-ATPase functions as a Na+-dependent K+(NH4+)-ATPase in apical membranes from rat distal colon. J. Biol. Chem. 274:19693-19698, 1999.

Laski, M.E., and Pressley, T.A. Aquaporin mediated water flux as a target for diuretic development. Sem. Nephrol. 19:533-550, 1999.

Efendiev, R., Bertorello, A.M., Pressley, T.A., Rousselot, M., Féraille, E., and Pedemonte, C.H. Simultaneous phosphorylation of Ser 11 and Ser 18 in the alpha-subunit promotes the recruitment of Na+,K+-ATPase molecules to the plasma membrane. Biochemistry 39:9884-9892, 2000.

Pressley, T.A., LeGrow, A.B., and Fielding, D.C. Hypothyroidism stimulates Na,K-ATPase in the rat thyroid gland. In: Na/K-ATPase and Related ATPases, eds. Taniguchi, K., and Kaya, S. Elsevier Science, Rotterdam, The Netherlands, pp. 733-734, 2000.

Pierre, S., Compe, E., Grillasca, J.-P., Plannells, R., Sampol, J., Pressley, T.A., and Maixent, J.-M. RT-PCR detection of Na,K-ATPase subunit isoforms in human umbilical vein endothelial cells (HUVEC): Evidence for the presence of alpha1 and beta3. Cell. Mol. Biol. 47:319-324, 2001

Pierre, S.V., Duran, M.J., Carr, D.L., and Pressley, T.A. Structure/function analysis of Na+-K+-ATPase central isoform-specific region: Involvement in PKC regulation. Am. J. Physiol. 283: F1066–F1074, 2002

Duran, M.J., Pierre, S.V., Carr, D.L., and Pressley, T.A. Role of the isoform-specific region of the Na,K-ATPase catalytic subunit. Ann. N.Y. Acad. Sci. 986: 258-259, 2003

Pierre, S.V., Duran, M.J., Carr, D.L., and Pressley, T.A. Structure/function analysis of Na,K-ATPase alpha1 and alpha2 central isoform-specific regions reveals their involvement in regulation by protein kinase C. Ann. N.Y. Acad. Sci. 986: 260-262, 2003

Carr, D.L., Laharrague, F., Kahn, B., Pressley, T.A., and Carr, J.A. Molecular characterization of a putative sodium/iodide symporter in the South African clawed frog, Xenopus laevis. Ann. N.Y. Acad. Sci. 986: 711-712, 2003

Pressley, T.A. Temperature Regulation: Lecture Notes, Handout, and Presentation. APS Archive of Teaching Resources Objects 438, 439, and 440, 2004

Duran, M.J., Pierre, S.V., Carr, D.L., and Pressley, T.A. The isoform-specific region of the Na,K-ATPase catalytic subunit: Role in enzyme kinetics and regulation by protein kinase C. Biochemistry 43: 16174-16183, 2004

Duran, M.J., Chosseler, M., and Pressley, T.A. Regulation of Na,K-pump-mediated transport by prolactin in cultured human prostate epithelial cells. Cell. Mol. Biol. 50:809-814, 2004

Pressley, T.A., Duran, M.J., and Pierre, S.V. Regions conferring isoform-specific function in the catalytic subunit of the Na,K-pump. Front. Biosci., 10:2018-2026, 2005

Pressley, T.A. Remembering Julius Allen. Cell. Mol. Biol. 53:OL941-OL942, 2007

Carroll, R.G, Matyas, M.L., Atwater, A.E., Doze, V., Faircloth, R., Finkenstadt, P., Goodman, B., Henriksen, E.J., Horwitz, B., Looft-Wilson, R., Madsen, B., Mody, J., Pelaez, N., and Thomas A. Pressley, T.A., APS undergraduate brainstorming summit report. Adv. Physiol. Edu. 31:380-386, 2007

Carr, D.L., Carr, J.A., Willis, R.E., and Pressley, T.A. A perchlorate sensitive iodide transporter in frogs. Gen. Comp. Endocrinol. 158:9-14, 2008

Pressley, T.A. The stoichiometry of the Na-K pump: one plus one doesn't equal one. Am. J. Physiol. 295:F1313, 2008

Sottejeau, Y., Belliard, A., Duran, M.J., Pressley, T.A., and Pierre, S.V. Critical role of the isoform-specific region in Na,K-ATPase trafficking and protein kinase C-dependent regulation. Biochemistry 49:3602-3610, 2010.

Submitted or In press

Carroll, R.G., Pressley, T.A., and Haramati, A. Physiological perspective of the role and value of basic sciences. J. Intl. Assoc. Med. Sci. Educ., in press.

Pressley, T.A., Limson, M., Byse, M., and Matyas, M.L. The heart race: A short-form, hands-on activity in cardiovascular physiology for museums and science festivals. Adv. Physiol. Educ., submitted.

In preparation

Pressley, T.A., and Nazaryan, K. Structural determinants of amino terminal processing in the alpha1 catalytic subunit of the Na,K-ATPase. FEBS Lett., submitted, revision in preparation.

Parish, L.P., Duran, M.J., Bouschet, A., and Pressley, T.A. Differential regulation of the Na,K-pump in human metastatic prostate cell lines.

Nonacademic Articles

Pressley, T.A. Flight logs on a budget. Soaring, 63(2):40-43, 1999.

Pressley, T.A. Region 10, South Plains Soaring Challenge 1998. Soaring, 63(2):9-10, 1999 (Contest Report).

Pressley, T.A. High and fast without an engine. Heat, sun, and sailplane racing on the South Plains of Texas. MUSC Medical Alumni TODAY, Winter 1999, pp. 14-15.

Pressley, T.A. Racing the Surreal: The Standard Class National Soaring Championship 2000. Soaring, 64(9):30-35, 2000 (Contest Report).

Pressley, T.A. Two New Contest Sites: Introducing Reese Center (near Lubbock, Texas) and Tonopah, Nevada, Part I. Soaring, 65(10):17-21, 2001 (Contest Report).

Pressley, T.A. The AeroKurier Online Contest: Not Just for Computer Nerds. 1-26 Association Website,, 2004.

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Last revised, March 25, 2011