Membrane Protein Core Laboratory
Introduction: The Membrane Protein Laboratory Core (MPLC), a shared facility of the Center for Membrane Protein Research (CMPR), houses equipment that is primarily accessible to the CMPR Faculty and their laboratory personnel, but is also available to Faculty throughout TTUHSC and TTU. The MPLC is equipped for the overexpression, purification and characterization of membrane proteins. Some of the equipment available includes digital gel-imaging systems (UV, visible and infrared), microscopes, spectrophotometer, fluorescence/absorbance microplate reader, microplate washer, luminometer, spectrofluorometer, refrigerated shaker incubators, probe sonicator, small and large volume microfluidizers, FPLC systems, phosphorescence lifetime spectrometers for luminescence resonance energy transfer measurements, rapid-mixing stop-flow system for absorbance, fluorescence and light-scattering determinations, ATR/FTIR spectrometer for secondary structure determination, a picosecond lifetime system, static, and dynamic light scattering instruments, centrifuges and ultracentrifuges, crystallization incubators and mosquito robot, automatic UV microscopy system for crystal analysis, Rigaku ScreenMachine for X-ray crystal screening and data collection, one- and two-photon confocal microscopy systems, high-throughput automatic frog-oocyte injector, liquid scintillation and gamma counters and an electron paramagnetic resonance spectrometer.
MPCL Contact Information
- Guillermo Altenberg, M.D., Ph.D., Director
- Luis Cuello, Ph.D., Associate Director