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Aging and Alzheimer's Disease Journal Club


This meeting takes  place in the GIA Conference Room, 4A125.   Multiple areas will be covered including, Geriatrics, Aging, Alzheimer's Disease and Obesity/Diabetes.  


Journal Club Schedule

Date Time       Presenter       Title
9/29/2015   Dr. Hemachandra Reddy

Gene regulation and DNA Damage in the Aging Human Brain

11/24/2015   Dr. Josh Lawrence

A novel nicotinic mechanism underlies β-amyloid induced neurotoxicity

12/22/2015   Dr. Ramesh Kandimalla

Association between Amylin and Amyloid-b Peptides in Plasma in the Context of Apolipoprotein E4 Allele

1/26/2016   Dr. Subodh Kumar

Genome-Wide Serum microRNA Expression Profiling Identifies Serum Biomarkers for Alzheimer's Disease

3/29/2016 10:00 AM Dr. Rui Wang

Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

4/26/2016 12:00 PM Dr. Murali Vijayan

Selective astrocytic endothelin-1 overexpression contributes to dementia associated with ischemic stroke by exaggerating astrocyte-derived amyloid secretion

5/31/2016 12:00 PM Dr. John Lawrence

Accelerated aging of the GABAergic septohippocampal pathway and decreased hippocampal rhythms in a mouse model of Alzheimer's disease

6/28/2016 12:00 PM Dr. Subodh Kumar

Regulates ApoE Lipidation and Amyloid-β_Metabolism in the Brain

7/26/16 12:00 PM Dr. Ramesh Kandimalla

Silencing of CDK5 Reduces Neurofibrillary Tangles in Transgenic Alzheimer's Mice

8/30/2016 12:00 PM Linda Yin

Meta-Analysis of Peripheral Blood Apolipoprotein E Levels in Alzheimer's Disease

9/6/2016 12:00 PM Dr. Meharvan Singh

Novel mechanisms of progesterone-induced brain protections:  Implications for Alzheimer's Disease

10/25/2016 12:00 PM Dr. Chandra Kuruva

Tau-Derived Hexapeptide 306VQIVYK311 Aggregrations Inhibitors:  Nitrocatechol Moiety as A Pharmacophore in Drug Design

11/22/2016 12:00 PM Dr. Rui Wang

Dysfunction of Somatostain-Positive Interneurons Associated with Memory Deficits in an Alzheimer's Disease Model

12/20/2016 12:00 PM Dr. J.A. Pradeepkiran

In Silico Modeling of Novel Drug Ligands for Treatment of Concussion Associated Tauopathy

01/24/2017 12:00 PM Dr. Jasvinder Bhatti

Genetic Analysis of New Mouse for Non-insulin-Dependent Diabetes

02/28/2017 12:00 PM Dr. Chandra Kuruva

Determinants of amyloid fibril degradation by the PDZ protease HTRA1

03/28/2017 12:00 PM Dr. Murali Vijayan

MicroRNA-103-1 Selectively Downregulates Brain NCX1 and Its Inhibition by Anti-miRNA Ameliorates Stroke Damage and Neurological Deficits

04/25/2017 12:00 PM Dr. Maria Manczak

Amyloid β-peptides interfere with mitochondrialpreprotein import competence by a coaggregation process

05/23/2017 12:00 PM Dr. Hemachandra Reddy

Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice

06/27/2017 2:00 PM Dr. Rui Wang

Dopamine neuronal loss contributes to memory and reward dysfunction

07/25/2017 12:00 PM Jake S. Smith
Dr. Subodh Kumar
Dr. Murali Vijayan

 Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules

11/28/2017 12:00 PM Dr. Hemachandra Reddy

PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.