2008 Chemistry Nobel Laureate,
William R. Kenan Jr. Professor and,
Chair of Biological Sciences
"As to the future, there are more experiments to do, music to play, people to enjoy, and surprises to catch me unaware," says Dr. Chalfie in his Nobel autobiography. Dr. Chalfie is widely recognized for his pioneering research on the 'green fluorescence protein' and is the recipient of 2008 Nobel Prize in chemistry along with Osamu Shimomura and Roger Y. Tsien. Dr. Chalfie is a chair of the Biological Sciences Department of Columbia University. His research focuses on addressing the neuronal cell fate determination and the molecular basis of mechanosensation, a sensory modality that underlies a variety of senses (e.g., touch, hearing, and balance). He is involved in studies on neuronal degeneration, microtubules and channel structure and function. These studies are facilitated through the development of new experimental methods, such as Green Fluorescent Protein and reconstituted GFP as gene and protein markers, and generation of temperature sensitive C. elegans gene. Dr. Chalfie has published over 200 papers of which at least 16 have over 100 citations.