Research Grants

Approved Grants Amarillo Campus
| 2007 | |
|---|---|
| Total Amount Awarded | |
| Sp17 Antigen Based Vaccine for Ovarian Cancer Principal Investigator: Maurizio Chiriva, PhD Co-Investigator: Marjorie Jenkins, MD Institutions: SOM, Amarillo & Lubbock | $20,000 |
| Cytochrome P450 Expression & Genotypes with Alzheimer’s Disease Principal Investigator: Majid Moridani, PhD Co-Investigator: Randolph Schiffer, PhD Institutions: SOP, Amarillo, Lubbock | $20,000 |
| Clinical Epidemiology of Preeclampsia in Texas Principal Investigator: Mulla Zuber, PhD Co-Investigators: Bahij Nuwayhid, MD Arthur Evans, MD James Van Hook, MD Moss Hampton, MD Institutions: SOM, El Paso, Amarillo, Odessa & Lubbock | $20,000 |
| Effect of green tea polyphenols on bone loss and Atherosclerosis Principal Investigator:Chwan-Li “Leslie” Shen, PhD Co-Investigator: Jia Shen-Wan, PhD Dale Dunn, MD Institutions:SOM Lubbock | $20,000 |
| Molecular Mechanisms associated with ovarian cancer metastasis Principal Investigator: Zhongan Dai, PhD Co-Investigator: William Robinson, MD Sean Tedjarati, MD Institutions: SOM Amarillo | $19,998 |
| Economic Differences Regarding Menopause & therapies in Hispanic women Principal Investigator: Joanna Wilson, DO Co-Investigator: Marjorie Jenkins, MD Institutions: SOM Amarillo | $3,750 |
| What patients know and believe about HPV vaccine Principal Investigator: Teresa Baker, MD Co-Investigator: Sean Tedjarati, MD Institutions: SOM Amarillo | $4,000 |
| 2006 | |
|---|---|
| Total Amount Awarded | |
| Gestational Diabetes Mellitus: Novel Screening Approaches Principal Investigator: Robert Kauffman, M.D. Co-Investigator: Glenn Anderson, PhD Institutions: SOM, SOP | $24,258.40 |
| Drug Resistance Biomarkers in the Human Breast Cancers Principal Investigator: U.S. Rao, PhD Co-Investigator: Kalkunte Srivenugopal, PhD Institutions: SOP | $25,000 |
| Gastrochesis: Incidence Epidemiology Principal Investigator: Bonna Benjamin, MD Co-Investigator: Institutions: SOP | $1,300 |
| Gender Differences in Decision Making Principal Investigator: K. MCCALL Institutions: SOP | $7,050 |
| 2005 | |
|---|---|
| Total Amount Awarded | |
| Osteoporosis Study Risk of Hip Fracture Principal Investigators: Marjorie Jenkins, M.D. Institutions: SOM, NWTHS | $ 55,600 |
| 2004 | |
|---|---|
| Total Amount Awarded | |
| Dual Strategy to Combat Toxicity and Improve Drug Efficacy in Breast Cancer Therapy Principal Investigator: K. Srivenugopal Institutions: SOP | $7500 |
| Molecular Targets to Inhibit Osteoporosis Principal Investigator: S. Lindsey Institutions: SOP | $25,000 |
| Estrogen Fatty ACYL COA Synthetase and Vascular Smooth Muscle Tone Combined with Proposed Role of Elfaoas in the Development of Post-Menopausal HTN Principal Investigator: M. Weis Institutions: SOP | $35,000 |
| Publication: Rohrer J and Rohland B. Psychosocial risk factors for obesity among women in a family planning clinic. BMC Family Practice Sept 2004, 5:20 DOI:10.1186/1471-2296-5-20; Article URL http://www.biomedcentral.com/1471-2296/5/20 | |
| Publication: Rohrer J and Young R. Self Esteem, stress and self-rated health in family planning clinic patients. BMC Family Practice June 2004, 5:11; Article URL http://www.biomedcentral.com/1471-2296/5/11 | |
| Publication: Crouch, Sonya, Spidel Celee M. & Lindsey, J. Suzanne (2004). HGF and ligation of avB5 integrin induce a novel, cancer cell-specific gene expression required for cell scattering. Experimental Cell Research, 292(2), 274-287. Online at www.sciencedirect.com | |
| Publication: Troy Phillips, J. Suzanne Lindsey (2004) Carcinoma cell-specific Mig-7: A new potential marker for circulating and migrating cancer cells. Oncology Reports 13: 37-44, 2005 | |
| Publication: Mehvar R and Chimalakonda A P. Hepatic disposition of cyclosporine A in isolated perfused rat livers. J Pharm Pharmaceut Sci Feb 2004:7(1):47-54 | |
| Publication: Rakhi B. Shah, Anitha Palamakula, Mansoor A. Khan. Cytotoxicity evaluation of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin; Journal of Pharmaceutical Sciences Volume 93, Issue 4, 2004. Pages 1070-1082 | |
| Publication: Anitha Palamakula, Mansoor Khan. Evaluation of cytotoxicity of oils used in coenzyme Q10 self-emulsifying drug delivery systems (SEDDS). International Journal of Pharmaceuticals 273 (2004) 63-73. Elsevier. | |
| 2003 | |
|---|---|
| Publication: Khan M.and Rakhi S B. Protection of Salmon Calcitonin Breakdown with Serine Proteases by Various Ovomucoid Specis for Oral Drug Delivery. Journal of Pharmaceutical Sciences, Vol. 93. Published online www.interscience.wiley.com DOI 10.1002/jps.10557 | |
| Publication: R.B. Shah, A. Siddiqui, G. Shah, M. A. Khan. A validated HPLC assay for simultaneous analysis of salmon calcitonin and duck ovomucoid. Pharmazie 58: 620-622 (2003) | |
| Publication: Fabio Grizzi, Barbara Franceschini, Maurizio Chiriva-Internati, Young Liu, Paul Hermonat, Nicola Dioguardi. Mast cells and human hepatocellular carcinoma; World Journal of Gastroenterology ISSN 1007-9327 CN 14-1219/R 2003 Jul; 9(7):1469-1473. | |
| 2002 | |
|---|---|
| Total Amount Awarded | |
| Investigation of the Role of Chondroitin Sulfate in Osteoarthritis: LC-ME Method Development Principal Investigator: R. Akins Institutions: SOP | $7500 |
| Coenzyme Q 10-Cancer Preventing Properties Principal Investigator: M. Khan Institutions: SOP | $7500 |
| Immune System to Kill Cancer Cells (Co-PI) Co-Investigator: S. Lindsey Institutions: SOP | $25,000 |
| AAV-DC Efficient Activation of Specific T Cells in Breast Cancer (Co-PI) Co-Investigator: J. Weidanz Institutions: SOP | $25,000 |
| Publication: Stephen E. Wright, Kathleen A Rewers-Felkins, Imelda Quinlin, Paul W Eldridge, Paul Zorsky, Panpit Klug, Catherine Phillips, Ramila Philip. Adopotive immunotherapy of mucin1 expressing adenocarcinomas with mucin1 stimulated human peripheral blood mononuclear cells; International Journal of Molecular Medicine 9:401-404, 2002. | |
| 2001 | |
|---|---|
| Total Amount Awarded | |
| The Relationship of Heliobacter pylori to Hyperemesis Gravidarum Principal Investigator: Abiodun Johnson, M.D. Co-Investigators: Thomas Myles, M.D. Institutions: SOM-Pedi & Ob/Gyn | $7,500 |
| Amarillo Area Health Professions Student Research Consortium Principal Investigator: Dennis B. Dove, M.D. Co-Investigators: Subcommittee on Student Research Institutions: SOM-Surgery | $7,000 |
| Osteoporosis Screening and Education in Community Pharmacies Using a Team (Not Completed) Principal Investigator: E. MacLaughlin Institutions: SOP Date of Publication: 2005 Eric J. MacLaughlin, Anitra A Maclaughlin, Kathleen Snella, Thomas Winston, David Fike, Cynthia Raehl. Osteoporosis screening and education in community pharmacies using a team approach; Pharmacotherapy 2005; 25(3):379-386 | $7460 |
| Treatment of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer with Mirtazapine (Not Completed) Principal Investigator: C. Herndon Institutions: SOP | $5500 |
| Improving the Care of Women with Alzheimer's Disease through a Multidisciplinary Intervention Program (Not Completed) Principal Investigator: C. Fernandez Institutions: SOP | $6000 |
| Effects of Equilin on Estradiol Metabolism (Not Completed) Principal Investigator: C. Fisher Institutions: SOP | $5580 |
| Regulation by Long Chain Fatty ACYL COA Synthetase in Human Coronary Endothelial Cells Principal Investigator: M. Weis Institutions: SOP Date of Publication: 2005 Margaret T Weis. Monica Brady, Mike Moore, Jason Crumley, John Stallone. Inhibiting long-chain fatty Acyl CoA synthetase does not increase Agonist-Induced release of Arachidonate Metabolites from human endothelial cells. J Vasc Res 2005;42:275-283 DOI: 10.1159/000085847. www.karger.com/jvr | $5500 |
| 2000 | |
|---|---|
| Total Amount Awarded | |
| Genes Induced by the Activated Protooncogens , MET Principal Investigator: S. Lindsey Institutions: SOP | $20,000 |
| Regulation of the High-Affinity Choline Transporter by Estrogen Principal Investigator: J. Stoll Institutions: SOP | $13,975 |
| Publication: Stephen W Wright, Lydia Kilinski, Sohel Talib, Karen E. Lowe, Janet S Burnside, Ji Yuan Wu, Nochol Dolby, Keneth E. Dombrowski, Jane Lebowski, Remila Philip. Cytotoxic T lymphocytes from humans with adenocarcinomas stimulate by native MUC1 mucin and a mucin peptide mutated at a glycosylation site; Journal of Immunotherapy 23(1)2-10 (2000) Lippincott Williams& Wilkins, Inc. | |
Approved Grants Permian Basin Campus
| 2007 |
|---|
| Hormonal Regulation of estrogen receptor expression in human breast cancer cells Principal Investigator: Gudmundur Thordarson, Ph.D. Co-Investigator: V. Daniel Castracane, Ph.D. |
| DNA repair based therapeutic strategies for BRCA1 mutant breast cancers Principal Investigator: Kalkunte S. Srivenugopal, Ph.D. Co-Investigators: Kyron Tamar, M.D. Brian T. Pruitt, M.D. |
| Adipokines and Gestational Diabetes Principal Investigators: V. Daniel Castracane, Ph.D. Robert R. Kauff man, M.D. |
| Amylin Responses to Exercise in Women During the Menstrual Cycle Principal Investigators: V. Daniel Castracane, Ph.D. Robert R. Kraemer, Ph.D. |
| Measures of Job Stress in Female Resident Physicians – What Do Their Spouses Think? Principal Investigator: Rama R. V. Chemitiganti, M.D. Co-Director: William R. Davis, M.D. |
| Repeat Pregnancy in Adolescents and Role of Provider Principal Investigator: R. Moss Hampton, M.D. |
| Role of 25-hydroxycholesterol in endometriosis Principal Investigator: James Hutson, Ph.D. Co-Investigator: R. Moss, Hampton, M.D |
| Inflammation and type 2 Diabetes Mellitus in postmenopausal Hispanics in West Texas Principal Investigator: Craig W. Spellman, D.O., Ph.D. Co-Investigators: Rama R.V. Chemitiganti, M.D. Walter McConathy, M.D. James K. Burks, M.D. |
Additional Research Grants:
- TTUHSC and partner UMC Southwest Cancer and Research Center, served as a national site for the study of Tamoxifen and Raloxifene, or STaR.
- Current funded research is investigating smoking in men and women cancer cells and molecular biology, genetics, breast cancer, gyneclogical oncology, lung cancer and more.