TTUHSC Laura W. Bush Institute for Women's Health
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Research Grants


Approved Grants Amarillo Campus

2007
Total Amount Awarded
Sp17 Antigen Based Vaccine for Ovarian Cancer
Principal Investigator: Maurizio Chiriva, PhD
Co-Investigator: Marjorie Jenkins, MD
Institutions: SOM, Amarillo & Lubbock
$20,000
Cytochrome P450 Expression & Genotypes with Alzheimer’s Disease
Principal Investigator: Majid Moridani, PhD
Co-Investigator: Randolph Schiffer, PhD
Institutions: SOP, Amarillo, Lubbock
$20,000
Clinical Epidemiology of Preeclampsia in Texas
Principal Investigator: Mulla Zuber, PhD
Co-Investigators: Bahij Nuwayhid, MD
Arthur Evans, MD
James Van Hook, MD
Moss Hampton, MD
Institutions: SOM, El Paso, Amarillo, Odessa & Lubbock
$20,000
Effect of green tea polyphenols on bone loss and Atherosclerosis
Principal Investigator:Chwan-Li “Leslie” Shen, PhD
Co-Investigator: Jia Shen-Wan, PhD
Dale Dunn, MD
Institutions:SOM Lubbock
$20,000
Molecular Mechanisms associated with ovarian cancer metastasis
Principal Investigator: Zhongan Dai, PhD
Co-Investigator: William Robinson, MD
Sean Tedjarati, MD
Institutions: SOM Amarillo
$19,998
Economic Differences Regarding Menopause & therapies in Hispanic women
Principal Investigator: Joanna Wilson, DO
Co-Investigator: Marjorie Jenkins, MD
Institutions: SOM Amarillo
$3,750
What patients know and believe about HPV vaccine
Principal Investigator: Teresa Baker, MD
Co-Investigator: Sean Tedjarati, MD
Institutions: SOM Amarillo
$4,000
2006
Total Amount Awarded
Gestational Diabetes Mellitus: Novel Screening Approaches
Principal Investigator: Robert Kauffman, M.D.
Co-Investigator: Glenn Anderson, PhD
Institutions: SOM, SOP
$24,258.40
Drug Resistance Biomarkers in the Human Breast Cancers
Principal Investigator: U.S. Rao, PhD
Co-Investigator: Kalkunte Srivenugopal, PhD
Institutions: SOP
$25,000
Gastrochesis: Incidence Epidemiology
Principal Investigator: Bonna Benjamin, MD
Co-Investigator:
Institutions: SOP
$1,300
Gender Differences in Decision Making
Principal Investigator: K. MCCALL
Institutions: SOP
$7,050
2005
Total Amount Awarded
Osteoporosis Study
Risk of Hip Fracture
Principal Investigators: Marjorie Jenkins, M.D.
Institutions: SOM, NWTHS
$ 55,600
2004
Total Amount Awarded
Dual Strategy to Combat Toxicity and Improve Drug Efficacy in Breast Cancer Therapy
Principal Investigator: K. Srivenugopal
Institutions: SOP
$7500
Molecular Targets to Inhibit Osteoporosis
Principal Investigator: S. Lindsey
Institutions: SOP
$25,000
Estrogen Fatty ACYL COA Synthetase and Vascular Smooth Muscle Tone Combined with Proposed Role of Elfaoas in the Development of Post-Menopausal HTN
Principal Investigator: M. Weis
Institutions: SOP
$35,000
Publication: Rohrer J and Rohland B. Psychosocial risk factors for obesity among women in a family planning clinic. BMC Family Practice Sept 2004, 5:20 DOI:10.1186/1471-2296-5-20;
Article URL http://www.biomedcentral.com/1471-2296/5/20
Publication: Rohrer J and Young R. Self Esteem, stress and self-rated health in family planning clinic patients. BMC Family Practice June 2004, 5:11; Article URL http://www.biomedcentral.com/1471-2296/5/11
Publication: Crouch, Sonya, Spidel Celee M. & Lindsey, J. Suzanne (2004). HGF and ligation of avB5 integrin induce a novel, cancer cell-specific gene expression required for cell scattering. Experimental Cell Research, 292(2), 274-287.  Online at www.sciencedirect.com
Publication: Troy Phillips, J. Suzanne Lindsey (2004) Carcinoma cell-specific Mig-7: A new potential marker for circulating and migrating cancer cells. Oncology Reports 13: 37-44, 2005
Publication: Mehvar R and Chimalakonda A P. Hepatic disposition of cyclosporine A in isolated perfused rat livers. J Pharm Pharmaceut Sci Feb 2004:7(1):47-54
Publication: Rakhi B. Shah, Anitha Palamakula, Mansoor A. Khan. Cytotoxicity evaluation of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin; Journal of Pharmaceutical Sciences Volume 93, Issue 4, 2004. Pages 1070-1082
Publication: Anitha Palamakula, Mansoor Khan. Evaluation of cytotoxicity of oils used in coenzyme Q10 self-emulsifying drug delivery systems (SEDDS). International Journal of Pharmaceuticals 273 (2004) 63-73. Elsevier.
2003
Publication: Khan M.and  Rakhi S B. Protection of Salmon Calcitonin Breakdown with Serine Proteases by Various Ovomucoid Specis for Oral Drug Delivery. Journal of Pharmaceutical Sciences, Vol. 93. Published online www.interscience.wiley.com DOI 10.1002/jps.10557
Publication: R.B. Shah, A. Siddiqui, G. Shah, M. A. Khan. A validated HPLC assay for simultaneous analysis of salmon calcitonin and duck ovomucoid. Pharmazie 58: 620-622 (2003)
Publication: Fabio Grizzi, Barbara Franceschini, Maurizio Chiriva-Internati, Young Liu, Paul Hermonat, Nicola Dioguardi. Mast cells and human hepatocellular carcinoma; World Journal of Gastroenterology ISSN 1007-9327 CN 14-1219/R 2003 Jul; 9(7):1469-1473.
2002
Total Amount Awarded
Investigation of the Role of Chondroitin Sulfate in Osteoarthritis: LC-ME Method Development
Principal Investigator: R. Akins
Institutions: SOP
$7500
Coenzyme Q 10-Cancer Preventing Properties
Principal Investigator: M. Khan
Institutions: SOP
$7500
Immune System to Kill Cancer Cells (Co-PI)
Co-Investigator: S. Lindsey
Institutions: SOP
$25,000
AAV-DC Efficient Activation of Specific T Cells in Breast Cancer (Co-PI)
Co-Investigator: J. Weidanz
Institutions: SOP
$25,000
Publication: Stephen E. Wright, Kathleen A Rewers-Felkins, Imelda Quinlin, Paul W Eldridge, Paul Zorsky, Panpit Klug, Catherine Phillips, Ramila Philip. Adopotive immunotherapy of mucin1 expressing adenocarcinomas with mucin1 stimulated human peripheral blood mononuclear cells; International Journal of Molecular Medicine 9:401-404, 2002.
2001
Total Amount Awarded
The Relationship of Heliobacter pylori to Hyperemesis Gravidarum
Principal Investigator: Abiodun Johnson, M.D.
Co-Investigators: Thomas Myles, M.D.
Institutions: SOM-Pedi & Ob/Gyn
$7,500
Amarillo Area Health Professions Student Research Consortium
Principal Investigator: Dennis B. Dove, M.D.
Co-Investigators: Subcommittee on Student Research
Institutions: SOM-Surgery
$7,000
Osteoporosis Screening and Education in Community Pharmacies Using a Team (Not Completed)
Principal Investigator: E. MacLaughlin
Institutions: SOP
Date of Publication: 2005
Eric J. MacLaughlin, Anitra A Maclaughlin, Kathleen Snella, Thomas Winston, David Fike, Cynthia Raehl. Osteoporosis screening and education in community pharmacies using a team approach; Pharmacotherapy 2005; 25(3):379-386
$7460
Treatment of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer with Mirtazapine (Not Completed)
Principal Investigator: C. Herndon
Institutions: SOP
$5500
Improving the Care of Women with Alzheimer's Disease through a Multidisciplinary Intervention Program (Not Completed)
Principal Investigator: C. Fernandez
Institutions: SOP
$6000
Effects of Equilin on Estradiol Metabolism (Not Completed)
Principal Investigator: C. Fisher
Institutions: SOP
$5580
Regulation by Long Chain Fatty ACYL COA Synthetase in Human Coronary Endothelial Cells
Principal Investigator: M. Weis
Institutions: SOP
Date of Publication: 2005
Margaret T Weis.
Monica Brady, Mike Moore, Jason Crumley, John Stallone. Inhibiting long-chain fatty Acyl CoA synthetase does not increase Agonist-Induced release of Arachidonate Metabolites from human endothelial cells. J Vasc Res 2005;42:275-283 DOI: 10.1159/000085847. www.karger.com/jvr
$5500
2000
Total Amount Awarded
Genes Induced by the Activated Protooncogens , MET
Principal Investigator: S. Lindsey
Institutions: SOP
$20,000
Regulation of the High-Affinity Choline Transporter by Estrogen
Principal Investigator: J. Stoll
Institutions: SOP
$13,975
Publication: Stephen W Wright, Lydia Kilinski, Sohel Talib, Karen E. Lowe, Janet S Burnside, Ji Yuan Wu, Nochol Dolby, Keneth E. Dombrowski, Jane Lebowski, Remila Philip. Cytotoxic T lymphocytes from humans with adenocarcinomas stimulate by native MUC1 mucin and a mucin peptide mutated at a glycosylation site; Journal of Immunotherapy 23(1)2-10 (2000) Lippincott Williams& Wilkins, Inc.


Approved Grants Permian Basin Campus

2007
Hormonal Regulation of estrogen receptor expression in human breast cancer cells
Principal Investigator: Gudmundur Thordarson, Ph.D.
Co-Investigator: V. Daniel Castracane, Ph.D.
DNA repair based therapeutic strategies for BRCA1 mutant breast cancers
Principal Investigator: Kalkunte S. Srivenugopal, Ph.D.
Co-Investigators: Kyron Tamar, M.D.
Brian T. Pruitt, M.D.
Adipokines and Gestational Diabetes
Principal Investigators: V. Daniel Castracane, Ph.D.
Robert R. Kauff man, M.D.
Amylin Responses to Exercise in Women During the Menstrual Cycle
Principal Investigators: V. Daniel Castracane, Ph.D.
Robert R. Kraemer, Ph.D.
Measures of Job Stress in Female Resident Physicians – What Do Their Spouses Think?
Principal Investigator: Rama R. V. Chemitiganti, M.D.
Co-Director: William R. Davis, M.D.
Repeat Pregnancy in Adolescents and Role of Provider
Principal Investigator: R. Moss Hampton, M.D.
Role of 25-hydroxycholesterol in endometriosis
Principal Investigator: James Hutson, Ph.D.
Co-Investigator: R. Moss, Hampton, M.D
Inflammation and type 2 Diabetes Mellitus in postmenopausal Hispanics in West Texas
Principal Investigator: Craig W. Spellman, D.O., Ph.D.
Co-Investigators: Rama R.V. Chemitiganti, M.D.
Walter McConathy, M.D.
James K. Burks, M.D.


Additional Research Grants: