Pharmaceutical Sciences

keshavarz
  • Graduate Student / Research Assistant
Lab Phone: 806-414-9249/9259
E-Mail: ali.keshavarz@ttuhsc.edu
Mail Address: 1300 S Coulter
Amarillo, TX 79106-1712

Biography

Ali Keshavarz completed his Doctoral degree in Pharmacy Practice from Tehran University of Medical Sciences and Health Services, Iran, in 2011. He joined the Graduate Program in Pharmaceutical Sciences as a PhD student in the fall of 2015, and is presently working in the laboratory of Dr. Fakhrul Ahsan with the Department of Pharmaceutical Sciences.

Education:

  • PharmD: Tehran University of Medical Sciences and Health Services, Iran, 2011

Research Interests:

Using Microfluidic chips to prepare nanoparticles and cell culture; Investigation on pulmonary disease treatment; Production of nanoparticles, pharmaceutical tablets by 3D printer; Intelligent drug nanoparticles delivery to specific sites using modern techniques such as magnetic carriers, and hydrogels; Production of drug nanoparticles and evaluation thereof using modern and economical techniques such as SCF (Supercritical Fluids); Production of controlled drug release systems by application of polymers, such as silica and biodegradable implants such as PLGA and analysis of the release kinetic by software like Sigma plot; Validation of drugs’ assay procedures using simple, accurate, and precise methods such as UV-spectrophotometry and HPLC; Preparation of lyophilized drugs by lyophilizer to enhance drug solubility.

Publications:

  • Kadry H, Al-Hilal TA, Keshavarz A, Alam F, Xu C, Joy A, Ahsan F. Multi-purposable filaments of HPMC for 3D printing of medications with tailored drug release and timed-absorption. Int J Pharm. 2018 Jun 10;544(1):285-296.
  • Rashid J, Nahar K, Raut S, Keshavarz A, Ahsan F. Fasudil and DETA NONOate, Loaded in a Peptide-Modified Liposomal Carrier, Slow PAH Progression upon Pulmonary Delivery. Mol Pharm. 2018 May 7;15(5):1755-1765.

Presentations:

  • Oral Presentation: Ali Keshavarz, Taslim A. Al-Hilal, Wei Li, and Fakhrul Ahsan. "Capturing, counting and identifying CECs: a potential diagnostic marker for patients with pulmonary arterial hypertension". American Association of Pharmaceutical Sciences “PharmSci360”, Washington, D.C., Nov.2018.
  • Ali Keshavarz, Ahmed Alobaida, Taslim A. Al-Hilal, and Fakhrul Ahsan. "An isolated perfused rat lung model for studying controlled and targeted release of fasudil, an anti‐PAH drug, from peptide grafted liposomal formulations". American Association of Pharmaceutical Sciences “PharmSci360”, Washington, D.C., November 2018.
  • Podium Presentation: Ali Keshavarz, Taslim Al-Hilal, Wei Li, Fakhrul Ahsan. "A micropattern-engraved two-compartment tissue-chip as a model for studying right ventricular hypertrophy induced by pulmonary arterial hypertension". Biomedical Engineering Society, Atlanta, GA; October 2018.
  • Ali Keshavarz, Taslim A. Al-Hilal, Wei Li and Fakhrul Ahsan. "A Micropattern-Engraved Two-Compartment Tissue-Chip to Model the Right Ventricle and Pulmonary Arteries as a Single Functional Unit for Studying PAH-Induced Right Ventricular Hypertrophy". Seventeenth Annual Research Days, TTUHSC School of Pharmacy, Amarillo, TX; June 2018.
  • Taslim A. Al-Hilal, Ali Keshavarz, Wei Li, and Fakhrul Ahsan. "Multi-Channel Chips to Simulate Pulmonary Arterial Hypertension (PAH) Pathophysiology and Screen Anti-PAH Drugs". MicroTAS Int'l Conf, Savannah, GA; October 2017. [Presented by Ali Keshavarz.]
  • Podium Presentation: Ali Keshavarz, Taslim A. Al-Hilal, and Fakhrul Ahsan. "Preparation of a precise microfluidic platform mimicking the respiratory tract bifurcations to study anti asthmatic drug efficacy". Sixteenth Annual Research Days, TTUHSC School of Pharmacy, Amarillo, TX; June 2017.
  • Ali Keshavarz, Taslim A. Al-Hilal, and Fakhrul Ahsan. "A microfluidic platform mimicking the bifurcating respiratory tract to assess the deposition of anti-asthma drugs". International Society of Aerosols in Medicine, Santa Fe, NM; June 2017.

Seminars:

  • 11/30/2018 "Two-compartment tissue-chips to model PAH-induced right ventricular hypertrophy"
  • 09/20/2017 "A microfluidic chip to emulate PAH-induced right-ventricular hypertrophy" [Oral Qualifying Exam public presentation, counted as Seminar credit]
  • 02/22/2017 "Deploying Microfluidic Technology and the Science of Bio-Printing in Pharmaceutics"

Awards/Scholarships:

  • American Association of Pharmaceutical Scientists Travelship Award [sponsored by Eli Lilly], AAPS “PharmSci360” Annual Meeting, Washington, D.C., November 2018.
  • Best Abstract Award, American Association of Pharmaceutical Scientists “PharmSci 360”, Washington, D.C., November 2018; abstract titled "An isolated perfused rat lung model for studying controlled and targeted release of fasudil, an anti-PAH drug, from peptide grafted liposomal formulations". (selected Aug.2018)
  • Best Abstract Award, American Association of Pharmaceutical Scientists “PharmSci 360”, Washington, D.C., November 2018; abstract titled "Capturing, counting and identifying CECs: a potential diagnostic marker for patients with pulmonary arterial hypertension". (selected Aug.2018)
  • International Foundation for Ethical Research (IFER) Fellowship, funded by the National Anti-Vivisection Society; project titled "A micropattern-engraved two-compartment tissue-chip as a non-animal model for studying right-ventricular hypertrophy induced by pulmonary arterial hypertension". (selected Oct.2018)

Memberships:

  • Graduate Association in Amarillo – Senate Representative, 2018-2019.
  • Graduate Association in Amarillo, 2015-present.

 

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