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Published Manuscripts

January 1, 2015 - December 31, 2015


  Thomas Abbruscato

Yang, L., Islam, M.R., Karamyan, V.T., and T.J. Abbruscato. In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment. Brain Research 1609, 1-11 (2015). 

Kaushik, K.S. Purushotham B.R. and Abbruscato, T.J. Nicotine pre-exposure reduces stroke-induced glucose transporter-1 activity at the bloodÐbrain barrier in mice. Fluids and Barriers of the CNS (In press, 2015). 

Aristotelis Astreinidis

Valianou M, Cox AM, Pichette B, Hartley S, Paladhi UR, Astrinidis A.Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle 14(3), 399-407 (2015). 

Rajan R, Karbowniczek M, Pugsley HR, Sabnani MK, Astrinidis A, La-Beck NM. Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry. Cytometry A (Epub ahead of print, 2015).

Amy Blaszczyk

Blaszczyk AT, Sleeper RB, Bailey TA, Duncan NB, McCarrell J, Clifford KM. Workarounds during the transcription of medication orders in the long-term care setting. Ann of Long-term Care: Clin Care Aging. 2015;23(7):33-37. (No PMID)

Blaszczyk AT, McGinnis K, Michaels HN, Nguyen TN. Is it time to call it quits on low-dose quetiapine? Consult Pharm. 2015;30(5):287-290. PMID: 25979128.

Luca Cucullo

Prasad S, Sajja RK, Park JH, Naik P, Kaisar MA, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015 Jul. 24;12(1):18. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC398

P. Naik, R.K. Sajja, S. Prasad, and L. Cucullo. Effect of Full Flavor and Denicotinized Cigarettes Exposure on the Brain Microvascular Endothelium: A Microarray-based Gene Expression Study using a Human Immortalized BBB Endothelial Cell Line. BMC Neurosci

R. K. Sajja and L. Cucullo. Altered glycaemia differentially modulates blood-brain barrier drug efflux transporter expression and activity. Neurosci Lett. 2015 May 14;598:59-65

M. A. Kaisar and L. Cucullo. OTC Antioxidant Products for the Treatment of Cardiovascular and other Disorders: Popular Myth or Fact? J Pharmacovigil 2015, 3(2) 3:e136R ISSN: 2329-6887

R. K. Sajja Kayla L. Green and L. Cucullo. Altered Nrf2 signaling mediates hypoglycemia-induced blood–brain barrier endothelial dysfunction. Plos One 2015 Mar 25;10(3)

Ravi K Sajja, P. Naik and L. Cucullo. Differential Cerebrovascular Toxicity of Various Tobacco Products: A Regulatory Perspective. Journal of Pharmacovigilance ISSN: 2329-6887, Jan 09, 2015

R.K. Sajja, S. Rahman, L. Cucullo. Drugs of Abuse and Blood-Brain Barrier Endothelial Dysfunction: A Focus on the Role of Oxidative Stress. JCBFM. (accepted 10-13-2015)

Kaisar MA, Prasad S, Cucullo L. Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial? Brain Res. 2015 Sep 26. pii: S0006-8993(15)00716-7. doi: 10.1016/j.brainres.2015.09.018. [Epub ahead of print] PMID: 26410779

Pooja Naik; Luca Cucullo. Pathobiology of Tobacco Smoking and Neurovascular Disorders: Untied Strings and Alternative Products Fluids and Barriers of the CNS. FBCN-D-15-00011R2, (In Press)

Nakia Duncan

Clifford KM, Duncan NA, Heinrich K, Shaw J. Update on managing generalized anxiety disorder in older adults. Journal of Gerontology Nursing 41(4):10-20 (2015).

Krystal Edwards

Minze MG, Koffarnus RL, Bailey TA, Diec S, Edwards KL. Sodium-glucose co-transporter 2 inhibitors: evidence and place in therapy. Expert Rev Endocrinol Metab. 2015;10(6):645-661. dio: 10.1586/17446651. 2015. 1099431.

Ronald Hall

Pasipanodya J, Hall RG, Gumbo T. In silico-derived formula for individualized micafungin dosing for obese patients in the age of deterministic chaos. Clinical Pharmacology & Therapeutics 97(3), 292-297 (2015).

Hall RG. Evolving larger. Dosing anti-tuberculosis (TB) drugs in an obese world. Curr Pharm Des 2015;21:1-4 (e-pub ahead of print). PMID 26112269

Lee YR, Houngue C, Hall RG. Treatment of community-acquired pneumonia. Expert Rev Anti Infect Ther 2015;19:1-13. PMID: 26091895

Hall RG & Michaels HN. Profile of tedizolid phosphate and its potential in the treatment of acute bacterial skin and skin structure infections. Infect Drug Resist 2015;8:75-82. PMID: 25960671

Bethany Ibach

Ibach BW, Loeber C, Shukry M, Hagemann TM, Harrison D and Johnson PN. Duration of intrathecal morphine effect in children with idiopathic scoliosis undergoing posterior spinal fusion. Journal of Opioid Management 11(4), 295-303 (2015).

Magdelena Karbowniczek

Patel B, Patel J, Cho JH, Manne S, Bonala S, Henske E, Roegiers F, Markiewski M, Karbowniczek M. Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex. Oncogene. 2015 Oct 5. doi: 10.1038/onc.2015.358. [Epub ahead of print] PubMed PMID: 26434588.

Sharma SK1, Chintala NK1, Vadrevu SK1, Patel J1, Karbowniczek M2, Markiewski MM2. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs.

Rajan R, Karbowniczek M, Pugsley HR, Sabnani MK, Astrinidis A, La-Beck NM. Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry. Cytometry A (Epub ahead of print, 2015).

Irene La-Beck

Sabnani MK, Rajan R, Rowland B, Mavinkurve V, Wood LM, Gabizon AA, La-Beck NM. Liposome promotion of tumor growth is associated with angiogenesis and inhibition of antitumor immune responses. Nanomedicine 11(2):259-62 (2015). Featured on Cover.

Rajan R, Karbowniczek M, Pugsley HR, Sabnani MK, Astrinidis A, La-Beck NM. Quantifying autophagosomes and autolysosomes in cells using imaging flow cytometry. Cytometry A (Epub ahead of print, 2015).

Young Lee

Lee YR1, Houngue C, Hall RG., Treatment of community-acquired pneumonia. Expert Rev Anti Infect Ther. 2015 Sep;13(9):1109-21. doi: 10.1586/14787210.2015.1060125. Epub 2015 Jun 19.

Devin Lowe

Lowe DB, Finke JH, Garcia JA, Storkus WJ. Vaccines in RCC: Clinical and Biological Relevance. In: Renal Cell Carcinoma: Molecular Targets & Clinical Applications, 3rd Edition, RM Bukowski, R Figlin, and R Motzer, (Eds.), Springer, 2015.

La-Beck NM, Jean GW, Huynh C, Alzghari SK, Lowe DB. Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy. Pharmacotherapy 35 (10):963-76, 2015.

Weidanz JA, Doll KL, Mohana-Sundaram S, Wichner T, Lowe DB, Gimlin S, Wawro Weidanz D, Magnusson R, Hawkins OE.Detection of human leukocyte antigen biomarkers in breast cancer utilizing label-free biosensor technology. J Vis Exp (97), 2015.

Livia Macedo

Macedo L, Sturpe DA, Haines ST, Layson-Wolf C, Tofade TS, and McPherson ML. An objective structured teaching exercise (OSTE) for preceptor development. Currents in Pharmacy Teaching and Learning 7, 627-634 (2015). http://dx.doi.org/10.1016/j.cptl.2015.06.

Eric MacLaughlin

Dominguez DG, Fike DS, MacLaughlin EJ, Zorek JA. A comparison of the validity of two instruments assessing health professional student perceptions of interprofessional education and practice. Journal of Interprofessional Care 29(2):144-149 (2015).

Zorek JA, Subash M, Fike DS, MacLaughlin AA, Young RB, Samiuddin M, MacLaughlin EJ. Impact of an interprofessional teaching clinic on preventive care services. Fam Med. 2015;47(7)558-561.

Dominguez DG, Fike DS, MacLaughlin EJ, Zorek JA. A comparison of the validity of two instruments assessing health professional student perceptions of interprofessional education and practice. J Interprof Care. 2015;29(2):144-149. doi: 10.3109/13561820.201

Maciej Markiewski

Sharma SK1, Chintala NK1, Vadrevu SK1, Patel J1, Karbowniczek M2, Markiewski MM2. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. http://www.ncbi.nlm.nih.gov/pubmed/25911761

Constantinos Mikelis

Mikelis CM, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams RH, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS. RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock. Nature Communications 10;6:6725 (2015).

Dillenburg-Pilla, P., Patel, V., Mikelis, C.M., Zarate-Blades, C.R., Amornphimoltham, P., Wang, Z., Martin, D., Leelahavanichkul, K., Doci, C.L., Dorsam, R., Masedunskas, A., Weigert, R., Molinolo, A.A. and Gutkind, J.S. SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis. FASEB Journal.

Doçi, C.L., Mikelis, C.M., Molinolo, A.A., Amornphimoltham, P., Lionakis, M.S., and Gutkind, J.S. Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma. Cancer Res. 2015 Jul 15;75(14):293

Molly Minze

Minze MG, Koffarnus RL, Bailey TA, Diec S, Edwards KL. Sodium-glucose co-transporter 2 inhibitors: evidence and place in therapy. Expert Rev Endocrinol Metab. 2015;10(6):645-661. dio: 10.1586/17446651. 2015. 1099431.

Janie Robles

Robles J, Pinal D, Seifert CF. Hospitalist Impact in Antibiotic Selection in Pediatric Community Acquired Staphylococcus Aureus Skin Infection. Pediat Therapeut 2015;5:2.

Robles J. Student Learning Contracts: Considerations for Implementation in Pharmacy Experiential Experiences. Pharma Care Health Sys. Special Issue: Innovations in Pharmacy Education 2015;2:3.

Charles Seifert

Hong MT, Seifert CF. Clinical Impact of Discordant Prescribing of Fluoroquinolones and Alternative Treatment in E. Coli Pyelonephritis. Journal of Pharmacy Practice (2015).

Hong MT, Seifert CF. Robles J, Pinal DI, Seifert CF. Hospitalist Impact in Antibiotic Selection in Pediatric Community Acquired Staphylococcus Aureus Skin Infection. Pediatrics and Therapeutics 2015;5:2. http://dx.doi.org/10.4172/2161-0665.1000243. (original research)

Seifert CF, Brown AT. IDSA or ACG Guidelines for Treatment for Clostridium difficile Infection: Which one to follow? The Reply (letter), The American Journal of Medicine, 2015;128 (4):Page e19. DOI: 10.1016/j.amjmed.2014.11.016.

Seifert CF, Brown AT. Proton Pump Inhibition May Promote Clostridium difficile Recurrences. The Reply (letter), The American Journal of Medicine, 2015:128 (4):Page e15. DOI: 10.1016/j.amjmed.11.017.

Quentin Smith

Morikawa A, Peereboom D, Thorsheim HR, Samala R, Balyan R, Murphy C, Lockman P, Simmons A, Weil R, Tabar V, Steeg P, Smith QR, Seidman A. Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study. Neuro Oncol  17(2): 289-95, 2015. PMID: 25015089

Spector R, Keep RF, Snodgrass S, Smith QR, Johanson CE. A balanced view of choroid plexus structure and function: focus on adult humans. Exp Neurol. 267:78-86, 2015. PMID:25747036

Puhalla S, Elmquist W, Freyer D, Kleinberg L, Adkins C, Lockman P, McGregor J, Muldoon L, Nesbit G, Peereboom D, Smith Q, Walker S, Neuwelt E. Unsanctifying the sanctuary: challenges and opportunities with brain metastases. Neuro Oncol. 2015 May 17(5) 639-51. PMID: 25846288

Levin VA, Tonge PJ, Gallo JM, Birtwistle MR, Dar AC, Iavarone A, Paddison PJ, Heffron TP, Elmquist WF, Lachowicz JE, Johnson TW, White FW, Sul J, Smith QR, Shen W,. Sarkaria JN, Samala R,.Wen PY, Berry DA, Petter RC. CNS Anticancer Drug Discovery and Development Conference White Paper. Neuro Oncol  17(6) 1-26, 2015

Sanjay Srivastava

Pramanik KC, Fofaria NM, Gupta P, Ranjan A, Kim SH and Srivastava SK. Inhibition of β-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-catenin/TCF complex: Critical role of STAT-3. Oncotarget, 10;6(13), 11.561- 11.574, (2015).

Fofaria NM and Srivastava SK. STAT-3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells. Carcinogenesis, 36,142-150 (2015).

Gupta P, Wright SE, and Srivastava SK. PEITC treatment suppresses myeloid derived tumor suppressor cells to inhibit breast tumor growth. OncoImmunology, 4:2, e981449-1-7, (2015).

Jung JH, Yun M, Choo EJ, Kim SH, Jeong MS, Jung DB, Lee H, Kim EO, Kato N, Kim B, Srivastava SK, Kaihatsu K, Kim SH A derivative of epigallocatechin-3-gallate induces apoptosis via SHP-1-mediated suppression of BCR-ABL and STAT3 signalling in chronic myelogenous leukaemia. Br.J. Pharmacol, 17.2 (14), 3.565 -3.578, (2015).

Kim B, Srivastava SK, Kim SH (2015). Caspase-9 as a therapeutic target for treating cancer. Expert Opinion on Therapeutic Targets 2015;19(1):113-27.

Fofaria NM, Ranjan A, Kim SH and Srivastava SK (2015). Mechanisms of the anticancer effects of isothiocyanates. The Enzymes, 37, 111-137.

Ranjan A, Fofaria NM, Kim SH, Srivastava SK. Modulation of signal transduction pathways by natural compounds in cancer. Chinese Journal of Natural Medicines, 2015, 13(10): 730-742.

Fofaria NM, Frederick DT, Sullivan RJ, Flaherty KT and Srivastava SK (2015). Overexpression of Mcl-1 responsible for resistance to vemurafinib in melanoma. Oncotarget, (In Press).

Paul Trippier

Zang T,1, Verma K, Chen M, Jin Y, Trippier PC, Penning TM. Screening baccharin analogs as selective inhibitors against type 5 17b-hydroxysteroid dehydrogenase (AKR1C3). Chemico-Biological Interactions 234:339-348 (2015).

ASSAY and Drug Development Technologies, Volume 13, Number 2, 2015, Mary Ann Liebert, Inc., DOI: 10.1089/adt.2014.1507.abstractsAssay and Drug Dev. Technol 2015, 13, 138-139

Nihar Kinarivala and Paul C. Trippier; Progress in the Development of Small Molecule Therapeutics for the Treatment of Neuronal Ceroid Lipofuscinoses (NCLs). J. Med. Chem. In Press. DOI: 10.1021/acs.jmedchem.5b01020.

 Published Book Chapters

January 1, 2015 - December 31, 2015

Luca Cucullo

R.K. Sajja, T.J. Abbruscato, L. Cucullo. “Blood-brain barrier dysfunction in diabetic brain: Molecular mechanisms and therapeutic opportunities”. Editors: Andres Costa and Eugenio Villalba; in. Horizons in Neuroscience Research. Volume 22, Chapter 3; pp. 139-168 Nova publications 09/01/2015

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