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Pharmacology and Neuroscience

Dr. Ali Roghani

Associate Professor of Pharmacology
Ph.D., University of Illinois, Urbana-Champaign, IL, 1986

Structure function, regulation and mechanism(s) of action of synaptic vesicle neurotransmitter transporters

The neurotransmitter acetylcholine (ACh) is necessary for various physiological processes such as muscle contraction and sleep. It has also been implicated in learning and memory and pathogenesis of Alzheimer’s and related neurological diseases.

Using cell & molecular and neurochemical methodologies, we are studying regulation of genes and proteins involved in ACh synthesis and metabolism. In a somewhat related project, we are employing molecular and behavioral approaches to identify and characterize genes involved in learning and memory in rats. In these studies, we rely on a behavioral response model called Pavlovian fear-condition learning.

For a complete list of publications by Ali Roghani in PubMed, click here

For further information contact Dr. Ali Roghani

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