TTUHSC School of Medicine
Internal Medicine

Internal Medicine

Faculty Listing » Nephrology


Sharma Prabhakar

Sharma Prabhakar, MD

Professor
Division Chief: Nephrology/ Fellowship Program Director/ Vice Chairman Department of Medicine

Office: 806-743-3155
Email: sharma.prabhakar@ttuhsc.edu

Patient Appointments:
806-743-3150
Clinic Location:
Texas Tech Pavilion, 2nd Floor

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Education:

  • Fellowship: All India Institute of Medical Sciences, 1983 University of Texas Southwestern,1987 Baylor college of medicine,1990
  • Residency: Baylor College of Medicine , 1989
  • Medical School: Osmania Medical College, Inida, M.D.,1989
  • Undergraduate School: Gandhi Medical College, India, B.S.,1976

Publications:

  • Nephropathy in a Novel Rat Model of Type II Diabetes is Associated with Oxidative Stress and Decreased Renal Nitric Oxide Production.. J AM Soc Neph, 18, 2945-2952, 2007
  • Nitric Oxide Synthase Inhibition and Kidney Injury. Current enzyme Inhibition, 3, 95-102, May 2007.
  • Nitric Oxide inhibitors in renal disorders. The Biomedical Scientist, UK. 2007, 51 (9) pages 721-729.
  • The Role of 5'-AMP-activated protein kinase (AMPK) in Diabetic Nephropathy: A new direction? Current Enzyme Inhibition, 5, 44-50, 2009.
  • “Angiotensin- nitric oxide interactions”. In “Advances in angiotensin research” pages 35-68, Nova-Science Publishers, New York, 2008.
  • “ Renal Disorders” and “Acid- Base and Electrolyte Disorders” in ‘Medical Secrets’ Ed by Mary Howard. Elsevier Co. Philadelphia Fifth Edition 2010.
  • Microarray meta-analysis identifies key genes involved in the pathophysiology of diabetic nephropathy. Genomics (revised manuscript in review) 2010.
  • “Role of vaso-active factors in the pathogenesis of diabetic nephropathy” in “Advances in pathogenesis of diabetic nephropathy” Edited by SS Prabhakar Nova Science Publishers, New York 2010.
  • “Experimental approaches to investigate diabetic nephropathy” in “Advances in pathogenesis of diabetic nephropathy” Edited by SS Prabhakar Nova Science Publishers, New York 2010.
  • Novel therapies in Diabetic Nephropathy. Nephrology Reviews DOI: 10.4081/nr.2011.e4 | Published: 2011-05-18 11:48:14.
  • Animal models of Diabetic Nephropathy. A comprehensive review. Journal of Investigative Medicine (in Press) 2011.
  • Angiotensin-Insulin cross talk- Implications for Insulin Resistance, Journal of Investigative Medicine. (Submitted) 2011.
  • Diabetic Glomerulopathy. In “Glomeulonephritis” ISBN 978-953-307-388-0 edited by INTECH open access publisher, August 2011.
  • Membranous Nephropathy in “Glomeulonephritis” ISBN 978-953-307-388-0 edited by INTECH open access publisher, August 2011
  • Focal and Segemental Glomerulosclerosis. In “Glomeulonephritis” ISBN 978-953-307-388-0 edited by INTECH open access publisher, August 2011.

Presentations:

  • Hematologic and renal recovery in a patient with light-chain multiple Myeloma and end-stage renal disease after two consecutive stem cell transplants.SSCI Meeting. New Orleans, La. Feb 9, 2007
  • Alpha lipoic acid ameliorates mitochonfrial oxidative stress but not activation of transforming growth factor beta in rat model of diabetic nephrology. World Congress of Nephrology, Rio De Janeiro, April 2007.
  • Improved Insulin resistance with Angiotensin Receptor Blockade is associated with Increased Tyrosine Phosphorylation of Insulin Receptor Substrate.The American Society of Nephrology Annual Meeting 2007.
  • Renal Nitric Oxide Expression of Angiotensin II type 2 receptors in ZSF rats. The American Society of Nephrology Annual Meeting 2007.
  • Urinary VEGF is elevated in early diabetic nephropathy. Presented at the Southern Regional meetings, New Orleans, 2008.
  • Functional genomics diabetic nephropathy in a newly characterized rat model. Presented at Experimental Biology meetings , San Diego 2008.
  • Regulation of endothelial nitric oxide synthase in early diabetic nephropathy. Presented at European Renal Association meetings , Stockholm, Sweden. May 2008.
  • Identification of functionally significant genes relevant to pathogenesis of diabetic nephropathy. Presented at the annual meetings of the American Society of Nephrology 2008.
  • Renoprotective Effects Of Angiotensin Blockade In Early Diabetic Nephropathy May Involve Modulation Of Podocin. Presented at the annual meetings of the American Society of Nephrology 2008.
  • Angiotensin Regulates AMP Activated Protein Kinase Activity In Diabetic Kidney. Presented at the annual meetings of the American Society of Nephrology 2008.
  • Angiotensin Blockade Increases Insulin Sensitivity by Upregulating Adiponectin Receptor Expression in type II Diabetes. Presented at the annual meetings of the American Society of Nephrology 2008.
  • PHOSPHORYLATED AMP-ACTIVATED PROTEIN KINASE DURING EARLY DIABETIC NEPHROPATHY. Accepted for oral presentation at the annual meetings of Southern Regional meetings, New Orleans Feb 2009.
  • An unusual case of resistant hypophosphatemia with Chiari malformation. Accepted for oral presentation at the annual meetings of Southern Regional meetings, New Orleans Feb 2009.
  • Intradialytic Modified Tai Chi Exercise Improves Balance In Hemodialysis Patients. Accepted for presentation at the annual meetings of the National Kidney Foundation, Nashville, TN, Mar 2009.
  • Short-term Modified Tai Chi Exercise Improves Quality Of Life In Hemodialysis Patients Accepted for presentation at annual meetings of American College of Sports Medicine, Seattle, May 2009.
  • Nitric Oxide Mediates Improved Insulin Resistance Resulting From Angiotensin Blockade In A Rat Model Of Metabolic Syndrome. Presented at the World Congress of Nephrology meetings at Milan Italy, 2009.
  • Curcumin inhibits VEGF in early nephropathy in a rat model of type II diabetes. Presented at the American Society of Nephrology San Diego, Oct 2009.
  • Insulin signaling in ZSF rats - evidence for angiotensin-insulin crosstalk. Presented at Nephrology Young Investigators Forum, Southern Regional meetings, New Orleans Feb 2010.
  • Diferuloylmethane (Curcumin) Potentiates Salutory Effects Of Angiotensin Blockade In Early Diabetic Kidney. Accepted for oral presentation at ERA-EDTA annual meetings Munich, Germany June 2010.
  • Diferuloylmethane (Curcumin) Augments Renoprotective Effects of Angiotensin Blockade in Diabetic Nephropathy by Ameliorating Mitochondrial Oxidative Stress, Presented at the annual meetings of American Society of Nephrology 2010.
  • Development of a novel mass spectrometry-based method for serum creatinine measurement in rodents. Presented at the annual meetings of American Society of Nephrology 2010.
  • Curcumin preserves renal function in early diabetic nephropathy by inhibiting VEGF expression in podocytes. Accepted for presentation at the nephrology Young Investigators’ Forum in Southern Regional meetings in New Orleans LA Feb 2011.
  • Reversible glycosuria in acute interstitial nephritis. A case report and review of literature. Accepted for oral presentation at the Southern Regional meetings in New Orleans LA Feb 2011.
  • Hyponatremia in hypopituitarism. Accepted for presentation at the Southern Regional meetings in New Orleans LA Feb 2011.
  • A novel approach to identifying the major disease processes associated with diabetic nephropathy Oral Presentation in Washington DC at the Experimental Biology meetings 2011.
  • A prospective population screening study for CKD and its risk factors in West Texas. The Texas CKD Study. Accepted for American Society of Nephrology Annual meetings 2011 Philadelphia PA.
  • Progressive Renal Failure, Proteinuria and Glomerulosclerosis in a Murine Model of Diabetic Nephropathy is associated with Mitochondrial Oxidative Stress. Accepted for American Society of Nephrology Annual meetings 2011 Philadelphia PA.
  Research Interests  

No research information available online at this time.