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Internal Medicine

Recent Publications

Fellows Publications

Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy.  Figueroa JA, Reidy A, Mirandola L, Trotter K, Suvorava N, Figueroa A, Konala V, Aulakh A, Littlefield L, Grizzi F, Rahman RL, Jenkins MR, Musgrove B, Radhi S, D'Cunha N, D'Cunha LN, Hermonat PL, Cobos E, Chiriva-Internati M. Int Rev Immunol. 2015 Mar;34(2): 154-87 doi: PMID 25901860

Nuclear Export as a Novel Therapeutic Target: The CRM1 Connection. Lu C, Figueroa JA, Liu Z, Konala V, Aulakh A, Verma R, Cobos E, Chiriva-Internati M, Gao W. Curr Cancer Drug Targets. 2015 PMID: 26324128

Treatment of Hepatic Epithelioid Hemangioendothelioma: Finding Uses for Thalidomide in a New Era of Medicine.  Soape MP, Verma R, Payne JD, Wachtel M, Hardwicke F, Cobos E. Case rep Gastrointest Med. 2015. Epub 2015 Jun 17. PMID 26167310

Sex-driven differences in immunological responses: challenges and opportunites for the immunotherapies of the third millennium. Mirandola L, Wade R, Verma R, Pena C, Hosiriluck N, Figueroa JA, Cobos E, Jenkins MR, Chiriva-Internati M. Int Rev Immunol. 2015 Mar;34(2):134-42. doi: PMID 25901858

The role of human papilloma virus (HPV) infection in non-anogential cancer and the promise of immunotherapy Cobos C, Figueroa JA, Mirandola L, Colombo M, Summers G, Figueroa A, Aulakh A, Konala V, Verma R, Riaz J, Wade R, Saadeh C, Rahman RL, Pandey A, Radhi S, Nguyen DD, Jenkins M, Chiriva-Internati M, Cobos E. Int Rev Immunol. 2014 Oct;33(5):383-401. doi:Epub 2014 May 8. PMID 24811210

Faculty Publications

Mast cells and the liver again process. Grizzi F, Di Crao G, Laghi L, Hermonat P, Mazzola P, Nguyen DD, Radhi S, Figueroa JA, Cobos E, Annoni G, Chiriva-Internati M. Immun Ageing. 2013 Mar 7;10(1):9.. PMID 23496863

Aging, cancer and cancer vaccines.  Mazzola P, Radhi S. Mirandola L, Annoni G, Jenkins M, Cobos E, Chiriva-Internati M. Immun Ageing. 2012 April 17;9(1)4.. PMID 22510392

Galectin-3C Inhibits Tumor Growth and Increases the Anticancer Activity of Bortezomib in a Murine Model of Human Multiple Myeloma. Mirandola L, Yu Y, Chui K, Jenkins MR, Cobos E, John CM, Chiriva-Internati M. PLoS One. 2011;6(7):e21811. Epub 2011 Jul 13. PMID: 21765917 [PubMed - in process] Free PMC Article Free full text Related citations

Cancer testis antigen, ropporin, is a potential target for multiple myeloma immunotherapy. Chiriva-Internati M, Mirandola L, Yu Y, Jenkins MR, Gornati R, Bernardini G, Gioia M, Chiaramonte R, Cannon MJ, Kast WM, Cobos E. J Immunother. 2011 Jul-Aug;34(6):490-9. PMID: 21654522 [PubMed - in process] Related citations

Notch-ing from T-cell to B-cell lymphoid malignancies. Mirandola L, Comi P, Cobos E, Kast WM, Chiriva-Internati M, Chiaramonte R. Cancer Lett. 2011 Sep 1;308(1):1-13. PMID: 21652011 [PubMed - in process] Related citations

Genistein inhibited proliferation and induced apoptosis in acute lymphoblastic leukemia, lymphoma and multiple myeloma cells in vitro. Li W, Frame LT, Hoo KA, Li Y, D'Cunha N, Cobos E. Leuk Lymphoma. 2011 Jul 13. [Epub ahead of print] PMID: 21749310 [PubMed - as supplied by publisher] Related citations

Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond. Chiriva-Internati M. Int Rev Immunol. 2011 Apr-Jun;30(2-3):138-49. PMID: 21557640 [PubMed - in process] Related citations

Cancer testis antigens: novel biomarkers and targetable proteins for ovarian cancer. Mirandola L, J Cannon M, Cobos E, Bernardini G, Jenkins MR, Kast WM, Chiriva-Internati M. Int Rev Immunol. 2011 Apr-Jun;30(2-3):127-37. PMID: 21557639 [PubMed - in process] Related citations

Prospects and challenges for immunotherapy of ovarian cancer--what can we learn from the tumor microenvironment? Chiriva-Internati M, Cobos E, Cannon MJ. Int Rev Immunol. 2011 Apr-Jun;30(2-3):67-70. PMID: 21557634 [PubMed - in process] Related citations

Understanding the cross-talk between ovarian tumors and immune cells: mechanisms for effective immunotherapies. Chiriva-Internati M, Mirandola L, Kast WM, Jenkins MR, Cobos E, Cannon MJ. Int Rev Immunol. 2011 Apr-Jun;30(2-3):71-86. PMID: 21557635 [PubMed - in process] Related citations

Identification of AKAP-4 as a new cancer/testis antigen for detection and immunotherapy of prostate cancer. Chiriva-Internati M, Yu Y, Mirandola L, D'Cunha N, Hardwicke F, Cannon MJ, Cobos E, Kast WM. Prostate. 2011 Apr 25. doi: 10.1002/pros.21400. [Epub ahead of print] PMID: 21520158 [PubMed - as supplied by publisher] Related citations

Dendritic cell vaccination against ovarian cancer--tipping the Treg/TH17 balance to therapeutic advantage? Cannon MJ, Goyne H, Stone PJ, Chiriva-Internati M. Expert Opin Biol Ther. 2011 Apr;11(4):441-5. Epub 2011 Jan 28. Review. PMID: 21271951 [PubMed - indexed for MEDLINE] Related citations

Nanotechnology and human health: risks and benefits. Cattaneo AG, Gornati R, Sabbioni E, Chiriva-Internati M, Cobos E, Jenkins MR, Bernardini G. J Appl Toxicol. 2010 Nov;30(8):730-44. doi: 10.1002/jat.1609. Review. PMID: 21117037 [PubMed - indexed for MEDLINE] Related citations

Ukrain affects pancreas cancer cell phenotype in vitro by targeting MMP-9 and intra-/extracellular SPARC expression. Funel N, Costa F, Pettinari L, Taddeo A, Sala A, Chiriva-Internati M, Cobos E, Colombo G, Milzani A, Campani D, Dalle-Donne I, Gagliano N. Pancreatology. 2010;10(5):545-52. Epub 2010 Oct 23. PMID: 20975318 [PubMed - indexed for MEDLINE] Related citations

Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer. Chiriva-Internati M, Yu Y, Mirandola L, Jenkins MR, Chapman C, Cannon M, Cobos E, Kast WM. PLoS One. 2010 May 12;5(5):e10471. PMID: 20485677 [PubMed - indexed for MEDLINE] Free PMC Article Free full text Related citations

An update on hematological malignancies. D'Cunha N, Cobos E. Tex Med. 2010 Sep 1;106(9):59-63. PMID: 20809446 [PubMed - in process] Related citations