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Pharmacology and Neuroscience

AMPA induces al large delayed increase in intracellular calcium in cerebellar Purkinje neurons. Top panel is before addition of AMPA. Bottom panel is 60 minutes following a 30 minute exposure to 30 micrmolar AMPA. Purkinje neurons (white arrowheads) were loaded with the AM-ester of Fluo-3.

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