Pharmacology and Neuroscience
Dr. Reid Norman
Professor of Pharmacology
Ph. D., Anatomy, Kansas University, 1971.
Central nervous system regulation of fertility in primates; influence of environmental
stress on gonadotropin secretion.
The goal of our research is to gain a better understanding of how the central nervous
system manages reproduction in primates. Estrogen (E) and testosterone (T) influence
how the brain controls the release of gonadotropic hormones from the pituitary. Our
hypothesis is that in addition to their role in feedback regulation of gonadotropins,
these gonadal steroids also influence how an animal interprets environmental events
that ultimately impact reproductive success. In higher primates, both psychological
and nutritional stress are environmental factors that can negatively affect reproduction.
However, it is not clear how these stressful stimuli interrupt gonadotropin secretion
and normal reproductive processes. Current inquiries in this laboratory focus on how
male and female primates respond differently to stress and how gonadal steroids affect
that response. Ongoing experiments include studies on the role that both NPY and vasopressin
have as mediators of the inhibitory effects of stress on GnRH release and the participation
of endogenous opiates in modulation of GnRH release from the hypothalamus.
For a complete list of publications by Reid Norman in PubMed, click here
For further information contact Dr. Reid L. Norman