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Pharmacology and Neuroscience


Dr. Susan E. Bergeson

Associate Professor
Department of Pharmacology and Neuroscience

Graduate Student Adviser

Ph.D., 1997 - Oregon Health & Science University

South Plains Alcohol & Addiction Research Center

Laura W. Bush Institute for Women's Health

Office:  5B148C         
Phone:  806-407-9930
Lab:  5B148A
Lab Phone:  806-743-3497
FAX:  806-743-2744



                                                 Current Projects | Current Funding | Publications

Current Projects

Genetics and Molecular Neurobiology of Alcohol Abuse and Alcoholism:

The Bergeson lab uses a combination of behavioral, biochemical, molecular and pharmacological approaches to study the genetics of predisposition, and the molecular neurobiology of alcohol abuse and alcoholism.  Through our use of bioinformatics technology, global transcriptional analyses of several genetic mouse models of alcohol drinking and dependence have uncovered new genes and biological pathways not previously known to be involved in alcohol-related behaviors and responses.  We have also recently uncovered that chromatin remodeling and miRNA expression play a role in the differential transcriptional response to alcohol drinking seen between adolescent and adult mice.   The current goals of the lab focus on:  1) alcohol-induced mRNA and miRNA transcriptome changes, 2) epigenetic consequences of alcohol drinking (histone modifications, H3.3 substitution and DNA methylation changes), 3) translational therapies targeting neuroimmune-related high alcohol consumption, 4) age-specific differences in alcohol mediated molecular neuroadaptation, 5) sexual dimorphic responses to alcohol, and in general, 6) the genetics of alcoholism.  Trainees have an opportunity to gain experience in a broad repertoire of laboratory technologies.

Current Funding  

NIH, 1R21 AA021142 - Neuroimmune Interactions in High Alcohol Drinking
Laura Bush Institute for Women's Health - Sex and Gender-Based Medicine Triads
Texas Tech University Transdisciplinary Research Academy - System-based transdisciplinary approaches by "omics and bioinformatics" tools to identify biomarkers of at risk and progression of type I diabetes.


For a list of publications by Dr. Bergeson in PubMed, click here

For further information contact: Dr. Susan E. Bergeson