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Profile for Zonghan Dai, PhD

Zonghan Dai

Zonghan Dai, PhD

  • Associate Professor
  • Director
  • Division Chief of Research
Office Phone: 806-356-4757 ext 243
Mail Address: 1406 S Coulter St
Amarillo TX 79106-1786

Research Interests

Actin dynamics, Bcr-Abl, Abl interactors (Abi), Signal Transduction, Cancer Metastasis, Breast Cancer, Leukemia, Cytoskeleton Remodeling, Growth Factors.

Teaching Interests

Cell Biology, Cytoskeleton, Signal Transduction, Molecular Biology, Transgenic Models, Molecular Oncology

Selected Publications:

  • Zhuang C, Tang H, Dissanaike SD, Cobos E, Tao Y, Dai Z. Cdk1-Mediated Phosphorylation Of Abi1 Attanuates Bcr-Abl-Induced F-Actin Assembly And Tyrosine Phosphorylation Of Wave Complex During Mitosis. J. Biol. Chem 2011;286(44):38614-26.
  • Li C, Liu B, Dai Z, Tao Y. Knockdown of VEGF Receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis, and growth of Clear Cell Renal Cell Carcinoma (CRCC).. Cancer Biology & Therapy 2011;12(10):872-80.
  • Yu W, Sun X, Tao Y, Dai Z. Inhibition of Class II Phosphoinositide 3-Kinase  Expression by p185Bcr-Abl Contributes to Impaired Chemotaxis and Aberrant homing of Leukemic cells.. Leukemia and Lymphoma 2010;51(6):1098-1107.
  • Sun X, Li C, Zhuang C, Gilmore WC, Cobos E, Tao Y, Dai Z. Abl Interactor 1 Regulates Src-Id1-Matrix Metalloproteinase 9 Axis and Is Required for Invadopodia Formation, Extracellular Matrix Degradation, and Tumor Growth of Human Breast Cancer Cells.. Carcinogenesis 2009;30:2109-16.
  • Li C, Sun X, Tao Y, Dai Z. Knockdown of Abl interactor 1 expression impairs invadopodia formation, tumor angiogenesis, and markedly slows tumor growth of breast cancer cells.. CANCER RESEARCH 2009;69(2):172S-173S .