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Profile for Paul Trippier, PhD

Paul Trippier

Paul Trippier, PhD

  • Assistant Professor Pharmaceutical Sci Amarillo
Office Phone: 806-414-9245
Mail Address: School of Pharmacy, 1300 S. Coulter
Amarillo TX 79106


Dr. Trippier joined the Pharmaceutical Sciences faculty in September 2012. He received his undergraduate degree with first class honors in Chemistry and Toxicology at the University of Hull (UK) undertaking undergraduate research on the design and synthesis of novel Angiotensin-converting enzyme inhibitors. Dr. Trippier received his Ph.D. in 2007 from the University of Oxford (UK) working on the total and diversity orientated synthesis of bioactive natural products. He completed postdoctoral research at The Welsh School of Pharmacy, Cardiff University (UK) in antiviral and anticancer medicinal chemistry. He joins the School of Pharmacy from Northwestern University, IL where he conducted research in the laboratory of Richard B. Silverman on the synthesis and intracellular target identification of potential new therapeutics for the treatment of neurodegenerative disease.

Selected Publications:

  • Trippier P, Wang H, Brookes PS. Mitochondrial Complex II Inhibitors/mKATP Activators: Chemical Tools to Probe the Mitochondria and a New Target of Action for Anticancer Drug Discovery?. Assay Drug Dev. Technol. 2015;13:138-139.
  • Zang T, Verma K, Chen M, Jin Y, Trippier P, Penning TM. Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3). Chem. Biol. Interact. 2015;234:339-48.
  • Kinarivala N, Trippier P. Exploration of Relative Chemoselectivity in the Hydrodechlorination of 2-Chloropyridines. Tetrahedron Lett. 2014;55:5386-5389.
  • Trippier P, Zhao K, Fox S, Schiefer I, Benmohamed R, Moran J, Kirsch D, Morimoto R, Silverman R. Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis. ACS Chem. Neurosci. 2014;5:823-829.
  • Trippier P. Synthetic strategies for the biotinylation of bioactive small molecules. ChemMedChem 2013;8:190-203.