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NEWSFLASH:         Research Days 2014


CCR cover Dr. Ming Hai-Wang, Professor in the Department of Biomedical Sciences, and his team’s recent publication, "Efficacy of Anti-RON Antibody Zt/g4–Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy," was published in the December 1, 2014 edition of the journal, Clinical Cancer Research.
 (Impact Factor 8.193)... READ ARTICLE

Dr. Wei Wang, Research Assistant Professor and Dr. Ruiwen Zhang, Professor, and their team identified a new anticancer agent that targets the cancer-causing gene MDM2, which is linked to poor response to treatment in breast cancer patients. The study, The Pyrido indole MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer Models, indicates that SP-141 is a novel targeted therapeutic agent that may especially benefit patients with advanced breast cancer. The article was accepted for publishing in the journal, Nature Communications (Impact Factor 10.742)... READ ARTICLE

ACS cover Dr. Ruiwen Zhang, Professor in the Department of Pharmaceutical Sciences, and his team identified a new class of MDM2 inhibitor called SP141, which may be further developed as a therapy for pancreatic cancer. The study, Identification of a New Class of MDM2 Inhibitor that Inhibits Growth of Orthotopic Pancreatic Tumors in Mice, was just accepted for publishing in the journal Gastroenterology (Impact Factor 13.926). READ ARTICLE

ACS cover A team of researchers led by Dr. Xinli Liu, Assistant Professor in the Department of Pharmaceutical Sciences, describe a novel finding of the mechanism and in vivo fate of tumor targeted nanoparticles in the journal ACS Nano, a leading journal in the field of nanoscience and nanotechnology with an impact factor of 12.06. The finding supports a new concept for understanding in vivo behavior of tumor targeted cancer nanomedicine. READ ARTICLE

CCS cover A study led by Dr. Maciej Markiewski, Associate Professor in the Department of Immunotherapeutics and Biotechnology at the School of Pharmacy in Abilene, has resulted in the discovery that the blocking of the single receptor present on the surface of special type of white blood cells can reduce or even prevent metastatic spread of cancer to the lungs. The study was published online in the May 1 issue of Cancer Research (Impact Factor 8.650). READ ARTICLE


Featured Grant:

Dr. Xinli Liu - NIH National Cancer Institute R15
Novel Therapeutics Targeting HER2 Positive Breast Cancer Brain Metastasis

New Grant Awards - Fall 2014

  • Dr. Eric MacLaughlin - MEDFOCUS NIH Subaward from University of Iowa
  • Dr. Ulrich Bickel - Therachon
  • Dr. Fakhrul Ahsan - Neofluidics
  • Alok Ranjan - Society of Toxicology Syngenta Fellowship
  • Pooja Naik - American Heart Association Predoctoral Fellowship
  • Dr. Sherry Luedtke - Discovery Labs
  • Dr. Richard Leff / Dr. Claudia Meek - Discovery Labs


2014 AAPS Pharmaceutical Research Outstanding Manuscript Award

PhR cover Quentin Smith, Professor in the Pharmaceutical Sciences Department and Dean of the School of Pharmacy, and Ramakrishna Samala, Kunal S. Taskar, Vinay Rudraraju, Rajendar K. Mittapalli, Helen R. Thorsheim, Julie Lockman, Brunilde Gril, Emily Hua, Diane Palmieri, Joseph W. Polli, Stephen Castellino, Stephen D. Rubin, Paul R. Lockman, and Patricia S. Steeg will be honored for the manuscript titled: Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer. AAPS photo The team will be formally recognized during the Opening Session of the 2014 AAPS Annual Meeting & Exposition held at the San Diego Convention Center in San Diego, California, on November 2, 2014. READ ARTICLE

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