TTUHSC School of Pharmacy

Office of Sciences


NEWSFLASH:         Research Days 2015


oncogene coverDr. Magdalena Karbowniczek, Associate Professor in the Department of Immunotheapeutics and Biotechnology in Abilene, and her team’s recent publication, “Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex." Dr. Karbowniczek’s laboratory studies the cellular and molecular mechanisms behind a rare disease tuberous sclerosis complex (TSC), which is caused by the inactivating mutations in tumor suppressor genes TSC1 and TSC2. The manuscript is scheduled for publication this year in the cancer journal Oncogene. (Impact Factor 8.459)... READ ARTICLE

Can also be found in BioQuick News

Dr. Wei Wang, Research Assistant Professor and Dr. Ruiwen Zhang, Professor, and their team identified a new anticancer agent that targets the cancer-causing gene MDM2, which is linked to poor response to treatment in breast cancer patients. The study, The Pyrido indole MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer Models, indicates that SP-141 is a novel targeted therapeutic agent that may especially benefit patients with advanced breast cancer. The article was accepted for publishing in the journal, Nature Communications (Impact Factor 10.742)... READ ARTICLE

ACS cover Dr. Ruiwen Zhang, Professor in the Department of Pharmaceutical Sciences, and his team identified a new class of MDM2 inhibitor called SP141, which may be further developed as a therapy for pancreatic cancer. The study, Identification of a New Class of MDM2 Inhibitor that Inhibits Growth of Orthotopic Pancreatic Tumors in Mice, was just accepted for publishing in the journal Gastroenterology (Impact Factor 13.926). READ ARTICLE


Dr. Magdalena Karbowniczek – DOD Office of Congressionally Directed Medical Research Programs (DOD CDMRP) - Identifying Mechanisms Initiating LAM and Angiomyolipoma In Tuberous Sclerosis Complex

Dr. Wei Wang – American Cancer Society - Targeting MDM2 Oncogene To Treat Breast Cancer

New Grants and Awards - Fall 2015

  • Dr. Xinli Liu – CPRIT High Impact / High Risk Research Grant
  • Dr. James Stoll – Laura Bush Institute for Women’s Health Centralized Seed Grant Program


Congratulations to
Dr. Thomas J. Abbruscato

Abbruscato Dr. Thomas Abbruscato has been appointed as chairperson of the Drug Discovery for the Nervous System Study Section, Center for Scientific Review, NIH, for the term beginning summer 2015 and ending in summer 2016.

2014 AAPS Pharmaceutical Research Outstanding Manuscript Award

PhR cover Quentin Smith, Professor in the Pharmaceutical Sciences Department and Dean of the School of Pharmacy, and Ramakrishna Samala, Kunal S. Taskar, Vinay Rudraraju, Rajendar K. Mittapalli, Helen R. Thorsheim, Julie Lockman, Brunilde Gril, Emily Hua, Diane Palmieri, Joseph W. Polli, Stephen Castellino, Stephen D. Rubin, Paul R. Lockman, and Patricia S. Steeg will be honored for the manuscript titled: Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer. AAPS photo The team will be formally recognized during the Opening Session of the 2014 AAPS Annual Meeting & Exposition held at the San Diego Convention Center in San Diego, California, on November 2, 2014. READ ARTICLE


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