In live cells and tissue imaging, a key technology is two photon laser scanning microscopy (TPLSM). It minimizes phototoxic effects and offers the possibility to image deep into tissues.
The Lumina XR system combines highly sensitive bioluminescence and fluorescence molecular optical imaging with the anatomical precision of digital x-ray.
A fluorescence microscope utilizes this characteristic shift to generate microscopic images to study unique structures and behaviors in cells and/or tissues. Combined with sensitive cameras, fluorescence microscopy can provide a user with both qualitative and quantitative data.
Confocal microscopy utilizes the basic principles of fluorescence microscopy, but unlike regular epifluorescence (widefield) microscopes, confocal microscopes take advantage of pinhole apertures to preferentially permit focused (or "aligned") light through each pinhole to provide a visual representation of the specimen.