Pharmaceutical Sciences

gupta_nehal
  • Graduate Student / Research Assistant
Lab Phone: 806-414-9223
E-Mail: nehal.gupta@ttuhsc.edu
Mail Address: 1406 S Coulter
Amarillo, TX 79106-1786

Biography

Nehal Gupta completed her Bachelor of Pharmacy degree from Devi Ahilya Vishwavidyalaya, India in 2012. She then received her Master of Pharmacy (Honors) degree in Pharmaceutics from Gujarat Technological University, India in 2014. Nehal joined the Graduate Program in Pharmaceutical Sciences as a PhD student in August 2014, and is presently working in the laboratory of Dr. Sanjay Srivastava with the Department of Pharmaceutical Sciences.

Education:

  • MPharm: Pharmaceutics, Gujarat Technological University, India, 2014
  • BPharm: Pharmacy, Devi Ahilya Vishwavidyalaya, India, 2012

Research Interests:

Evaluation of in vivo Efficacy of New Agents against Breast Cancer in Mouse Xenograft Models.

Publications:

  • Verma K, Gupta N, Zang T, Wangtrakuldee P, Srivastava SK, Penning TM, Trippier PC. AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells. Mol Cancer Ther. 2018 Jun 11. pii: molcanther.1023.2017.
  • Kim CG, Lee H, Gupta N, Ramachandran S, Kaushik I, Srivastava S, Kim SH, Srivastava SK. Role of Forkhead Box Class O proteins in cancer progression and metastasis. Semin Cancer Biol. 2017 Aug 1. pii: S1044-579X(17)30092-5.
  • Kshitij Verma, Tianzhu Zang, Nehal Gupta, Travor M. Penning, and Paul C. Trippier. "Selective AKR1C3 Inhibitors Potentiate Chemothrapeutic Activity in Multiple Acute Myeloid Leukemia (AML) Cell Lines." ACS Med. Chem. Lett. 2016 Jun 22;7(8):774-9.

Presentations:

   Before Admission to GPPS:

  • Gupta Nehal, Chavda Vivek, Soniwala M M, Chavda J R. "Lipid-based delivery systems: One step ahead in improving solubility of poorly soluble drugs". Nirma Institute of Pharmacy International Conference, Nirma University, Ahmedabad, India; January 2013.

   After Admission to GPPS:

  • PODIUM PRESENTATION: Nehal Gupta and Sanjay K. Srivastava. "Atovaquone: An Anti-Protozoal, Antimalarial Drug Suppresses Breast Tumor Growth by Inhibiting Her2/b-Catenin Signaling". TTUHSC School of Pharmacy, Research Days, Amarillo, TX; June 2018.
  • Nehal Gupta, Stephen Wright, Sanjay K. Srivastava. "Atovaquone suppresses triple negative breast tumor growth by inhibiting myeloid derived suppressor cells". American Association for Cancer Research, Chicago, IL; April 2018.
  • PODIUM PRESENTATION: Nehal Gupta and Sanjay K. Srivastava. "Atovaquone: An anti-protozoal, antimalarial drug suppresses breast tumor growth by inhibiting HER2/β-catenin signaling". Society of Toxicology Annual Meeting, San Antonio, TX; March 2018.
  • Nehal Gupta, Parul Gupta and Sanjay Srivastava. "Novel therapeutic approach to overcome paclitaxel resistance in breast cancer by targeting HER2/β-catenin signaling". American Association of Pharmaceutical Scientists, San Diego, CA; November 2017.
  • Nehal Gupta, Parul Gupta, Sanjay K. Srivastava. “Inhibition of HER2/beta-Catenin signaling by Penfluridol overcomes resistance to paclitaxel in breast cancer”. Sixteenth Annual Research Days, TTUHSC School of Pharmacy, Amarillo TX; June 2017.
  • Nehal Gupta, Parul Gupta, Sanjay Srivastava. "Penfluridol overcomes paclitaxel resistance by inhibition of HER2/[beta]-catenin signaling in breast cancer model." American Association of Pharmaceutical Scientists, National Biotechnology Conference, San Diego, CA; May 2017.
  • Nehal Gupta, Parul Gupta and Sanjay Srivastava. "Inhibition of HER2/β-catenin signaling by penfluridol overcomes resistance to paclitaxel in breast cancer". American Association for Cancer Research, Washington, D.C.; April 2017.
  • Nehal Gupta, Parul Gupta and Sanjay Srivastava. "Penfluridol Reduces Paclitaxel Resistance in Breast Cancer by Inhibiting HER2/β-catenin Signaling". Society of Toxicology, Baltimore, MD; March 2017.
  • Podium Presentation: Nehal Gupta, Parul Gupta, Sanjay Srivastava. "Penfluridol Reduces Paclitaxel Resistance in Breast Cancer by Inhibiting HER2/ß-Catenin Signaling". Student Research Week, TTUHSC Graduate School of Biomedical Sciences, Lubbock; March 2017.
  • Nehal Gupta, Parul Gupta and Sanjay Srivastava. "Penfluridol Reduces Paclitaxel Resistance by inhibiting HER2/beta-catenin signaling". American Association of Pharmaceutical Scientists, Denver, CO; November 2016.
  • Podium Presentation: Nehal Gupta, Parul Gupta and Sanjay Srivastava. "Penfluridol Reduces Paclitaxel Resistance in Breast Cancer by Inhibiting HER2/β-Catenin Signaling". Lone Star Regional Chapter of the Society of Toxicology, Waco, TX; October 2016.
  • Nehal Gupta, Nehal Gupta, Parul Gupta and Sanjay K. Srivastava. “Penfluridol Reduces Paclitaxel Resistance in Breast Cancer by Inhibiting HER2/β-Catenin Signaling.” Fifteenth Annual Research Days, TTUHSC School of Pharmacy, Amarillo, TX; June 2016.

Seminars:

  • 10/25/2017 "Novel therapeutic approach to overcome paclitaxel resistance in breast cancer by targeting HER2/β-catenin signaling"
  • 10/26/2016 "Atovaquone: An anti-protozoal drug for management of breast cancer" [Oral Qualifying Exam, public presentation]
  • 10/07/2015 "Pseudolaric Acid B: A Potential Novel Chemotherapeutic Agent for Prostate Cancer"

Awards/Scholarships:

  • Mary Lou Clements-Mann Scholarship, TTUHSC Graduate School of Biomedical Sciences, Fall 2018.
  • Biotechnology Specialty Section [BTTS] Student Achievement Award, Society of Toxicology, San Antonio, TX; March 2018.
  • Toxicologic and Exploratory Pathology Specialty Section (TEPSS) Charles River Travel Award, Society of Tosicology, San Antonio, TX; March 2018.
  • TTUHSC Graduate School of Biomedical Sciences (GSBS) Dean's Scholars Award, Fall 2017 (applied 12/01/2017).
  • AAPS Student Chapter, Travel Award, American Association of Pharmaceutical Scientists (AAPS), San Diego, CA; November 2017.
  • Sheldon D. Murphy Mechanisms Specialty Section (MSS) Student Travel Endowment Award, Society of Toxicology MSS, Baltimore, MD; March 2017.
  • Abstract First Place Graduate Student Winner, 2017 Dharm V. Singh Carcinogenesis Awards Fund, Society of Toxicology 56th Annual Meeting, Carcinogenesis Specialty Section, Baltimore, MD; March 2017.
  • Graduate Student Travel Support Award, Society of Toxicology, 56th Annual Meeting, Baltimore, MD; March 2017. [rec'd Dec'16]
  • Travel Award, American Association of Pharmaceutical Sciences, Student Chapter; November 2016.
  • Mary Lou Clements-Mann Scholarship, TTUHSC Graduate School of Biomedical Sciences; October 2016.
  • Best Podium Presentation Award, Lone Star Regional Chapter of Society of Toxicology (LSSOT), Waco, Texas; October 2016.

Memberships:

  • Graduate Student Association in Amarillo - President, 2017-2018.
  • Graduate Student Association in Amarillo - Treasurer, 2016-2017.
  • Graduate Student Association in Amarillo - Historian, 2015-2016
  • Graduate Student Association in Amarillo, 2014 - present
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