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TTUHSC Image Analysis Core Facility

Mission

The TTUHSC Imaging Center provides state-of-the-art instrumentation for high-resolution light microscopic imaging.  Expertise and advice is available for the design of experiments involving these techniques; and for the development of grants and manuscripts involving high-resolution light microscopic technologies. 

Services and Available Equipment

The imaging facility has a IVIS Lumina XR from the Caliper Life Sciences for real time tracking of cells expressing bioluminescent or fluorescent proteins simultaneously with X-ray digital imaging technology for living mice.  We also have two fully equipped laser scanning confocal microscopes.  One of these confocal microscopes is a newly acquired Nikon Ti-E microscope with A1 confocal and STORM super resolution.  The other is a Zeiss LSM 510/Meta confocal system attached to both inverted and upright microscopes.  The Nikon system is equipped to perform spectral imaging experiments, TIRF and FRAP.  A high temporal and spatial resolution EMCCD camera is attached to this system.  The microscope is also equipped with a stage-top environmental chamber in which precision temperature incubations can be performed.  In addition, we also have upright and inverted fluorescence microscopes attached to a CCD camera for routine observation of stained (fluorescence) or unstained (Differential Interference Contrast, DIC) specimens.  Additional equipment available in the Image Analysis Core Facility include a Meso Scale Discover Sector Imager that uses multi-array approaches enabling the detection of bio-markers in single and multiplex formats and a Typhoon FLA 9000 Bio-molecular Imager to image and quantify proteins, nucleic acids, and other molecules using filmless autoradiography, fluorescence, chemifluorescence, and gel documentation.  Click here for photos of equipment.  Click here for description of equipment.

To see other items of shared equipment at the TTUHSC please click here.

 

Contact Information

Dr. Martinez-Zaguilan is the director of the imaging center and an Associate Professor in the Department of Cell Physiology and Molecular Biophysics.  CVs (Martinez-Zaguilan

Email - raul.martinez-zaguilan@ttuhsc.edu 

Telephone - (806) 743-2562

Imaging Center Telephone - (806)743-4624

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