Pharmacology and Neuroscience
Dr. Ali Roghani
Associate Professor of Pharmacology
Ph.D., University of Illinois, Urbana-Champaign, IL, 1986
Structure function, regulation and mechanism(s) of action of synaptic vesicle neurotransmitter
The neurotransmitter acetylcholine (ACh) is necessary for various physiological processes
such as muscle contraction and sleep. It has also been implicated in learning and
memory and pathogenesis of Alzheimer’s and related neurological diseases.
Using cell & molecular and neurochemical methodologies, we are studying regulation
of genes and proteins involved in ACh synthesis and metabolism. In a somewhat related
project, we are employing molecular and behavioral approaches to identify and characterize
genes involved in learning and memory in rats. In these studies, we rely on a behavioral
response model called Pavlovian fear-condition learning.
For a complete list of publications by Ali Roghani in PubMed, click here
For further information contact Dr. Ali Roghani