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2014 SOM Student Summer Research Program

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Program Description

The School of Medicine Student Summer Research Program – 2014 is an 8-week program from June 9 to August 1 designed to help students gain experience in an area of research interest. First-year medical students in Lubbock are encouraged to coordinate with interested faculty members on project proposals that are to be submitted for approval to the Office of the Dean. A stipend in the total amount of $2,240 will be paid to each participating student in accordance with this guideline, and students are required to present information regarding summer research activities during the Student Research Week in the Spring 2015.

Introductory Lectures: Orientation to Clinical Research

This short lecture series will be offered by the Clinical Research Institute and will serve as an introduction to students' clinical research experience this summer. Students are expected to attend. These lectures provide background information on protocol development, IRB submission, function of the IRB, regulations and reasons for them, consenting subjects, etc.

Summer Accelerated Biomedical Research Program Seminar Series

Students are also expected to attend the SABR program seminar series starting in June 12, 2014.

Proposal/Project Abstract

The Student Summer Research Project Proposal Form should be filled out and submitted to the Office of the Dean and the Associate Dean for Research by May 9, 2014. Preferably, a form is submitted jointly by a student and faculty member who have coordinated the details of a research project for the summer; however, forms will be received from an individual for possible research projects. The Office of the Dean and the Associate Dean for Research will coordinate to assist in locating and matching interested students and faculty. Note: The proposed project should have appropriate institutional approval (IRB, IACUC, etc.) prior to the start of the program.

Download Student Summer Research Project Proposal Form

Summer Research

Matching Opportunities (Projects and Faculty Mentors)

Faculty Mentor



Potential Project Description



Contact Information



Potential Positions



Ihsan, Al-Khalil, M.D.
Pediatric Hematology/Oncology

The cure rate for cancer in children is around 80%. One project will be searching for late effects of chemotherapy and radiation on surviving cancer patients, children and adults. These effects are most likely on the CNS and endocrine system. There is also increased risk of a second malignancy. Over the summer, data will be collected from cancer patients (both children and adult) who survived pediatric cancer and analyze any lingering effects due to the chemotherapy and radiation. Also, the rate of second malignancy will be analyzed.

Due to the toxic effects of chemotherapy, targeted therapy has been utilized in adults. A second project will analyze the effects of targeted therapy on children as well for future treatment to avoid toxicity due to chemotherapy. This will entail the search for targeted therapy options and the mechanisms of their action on gross disease and minimum residual disease. From these mechanisms, a hypothesis will be formulated on which cancers targeted therapies can be used against.

Ihsan Al-Khalil, M.D.
ihsan.al-khalil@ttuhsc.edu
or 743-2244

1-2

Pablo Artigas, Ph.D.
Cell Physiology and Molecular Biophysics

Will study tissue specific regulation of Na/K pumps by kinases and regulatory subunits. We will use electrophysiological techniques in combination with fluorescence microscopy to study the modulation of protein-protein interactions by kinases.

Pablo Artigas, Ph.D.
pablo.artigas@ttuhsc.edu
or 743-3170

1

Ben Baronia, M.D.
Surgery

Neurosurgery projects.

Ben Baronia, M.D.
ben.c.baronia@ttuhsc.edu
or 743-2370

1

Susan Bergeson, Ph.D.
Pharmacology and Neuroscience

 Various assignments.

Filled

2

Kumuda Das, M.Sc., Ph.D.
Anesthesiology

Research methodology and development of hypothesis-driven research. The major aim is to understand how cardiomyocytes and the endothelial cells in the heart communicate in stress situations such as myocardial infarction induced by reperfusion injury. The project involves cell culture of primary endothelial cells and embryonic cardiomyocytes and determination of mechanism of secretion of soluble factors from endothelial cells that binds to receptors on cardiomyocytes. The techniques involve western analysis, real-time PCR, and cell culture methods.

Kumuda Das, M.Sc., Ph.D.
kumuda.das@ttuhscedu
Brandon Salinas
brandon.salinas@ttuhsc.edu
or 743-2981, ext. 230

2

Sharmila Dissinake, M.D.
Surgery

Various assignments.

Positions filled

3

David Edwards, M.D.
Family Medicine

There are tentative plans to work with the Residency Research Network of Texas (RRNeT) this summer to conduct a study entitled, "Patients' Understanding of Their Disease." This study will utilize the Information-Motivation-Behavioral Skills Model in obtaining questionnaire data from patients with diabetes and/or hypertension. Outcomes measured will include hemoglobin A1C values, blood pressures, and body mass indexes.

David Edwards, M.D.
david.s.edwards@ttuhscedu
or 743-2757

1

Jerry Grimes, M.D.
Orthopaedic Surgery

A retrospective review of Orthopaedic patients to evaluate the effectiveness of a change in surgical protocols. Extensive chart review and ability to discriminate outcomes from Orthopaedic notes. Another activity involves a study designed with vitamin C.

Positions filled

2

Abdul Hamood, Ph.D.
Immunology and Molecular Microbiology

Research in our laboratory is focused on: 1) the development of simple but novel models to examine biofilm development by different bacterial pathogens (specifically wound pathogens). Within the last few years, we have developed the in vitro two and three dimensional models to examine biofilm development in burned tissues; 2) the utilization of in vivo models to examine the effectiveness of antimicrobial coated devices in inhibiting biofilm development; and 3) the development of suitable models that mimic conditions at different Pseudomonas aeruginosa infection sites.

Abdul Hamood
abdul.hamood@ttuhsc.edu
or 743-1707

1

Allan Haynes, M.D.
Urology

Review of prostate biopsy patients correlating prostate symptoms scores with risk of positive biopsy for cancer.

Allan Haynes, M.D.
allan.haynes@ttuhsc.edu
or 743-1810

2

Michaela Jansen, Ph.D.
Cell Physiology & Molecular Biophysics

Research in the Jansen laboratory focuses on structure and function studies of diverse membrane proteins, specifically, ligand-gated ion channels and transporters. We use biophysical (electrophysiology, spectroscopy, X-ray crystallography) and biochemical methods to study these proteins at a molecular level. We are especially interested in the superfamily of pentameric ligand-gated ion channels (pLGIC) that includes the nACh, GABA, 5HT3, and Gly families. The pLGICs function mainly as neurotransmitter receptors, transforming the chemical signal contained in the neurotransmitter into an electrical signal.

Michaela Jansen, Ph.D.
michaela.jansen@ttuhscedu
or 743-4059

1

Matthew E. Lambert, Ph.D.
Rural and Community Health

Students will have the opportunity to develop a research protocol utilizing data collected for our community-based research project, Project FRONTIER, to examine health and aging in rural West Texas populations.

Cathy Hudson
catherine.hudson@ttuhsc.edu
or 743-5601

1-2

Laszlo Nagy, M.D.
Pediatric Neurology

Various assignments.

Laszlo Nagy, M.D.
laszlo.nagy@ttuhscedu
Tanya Lair
tanya.lair@ttuhsc.edu
or 743-7700

1

Kim Peck, M.D.
Associate Dean of Admissions and Diversity

Research will be conducted in two areas of interest:

  • Impact of Undergraduate Course Type on performance in TTUHSC SOM Curriculum Years 1 and 2
  • Factors Affecting TTUHSC School of Medicine Recruitment and Retention of Women Students

Position filled

1

Jose Perez-Zoghbi, M.D.
Cell Physiology & Molecular Biophysics

Project is related to asthma.

Position filled

1

Patrick Reynolds, M.D., Ph.D.
Cell Biology & Biochemistry

Cancer drug development, including models of cancer for drug testing

Patrick Reynolds, M.D., Ph.D.
patrick.reynolds@ttuhscedu
Jennifer Ockerstrom
jennifer.ockerstrom@ttuhsc.edu
or 743-1558

1-2

Departmental Responsibilities

Processing of all paperwork to ensure appropriate payment of stipends will be the responsibility of a participating department. Steps to be taken are:

  1. Process an ePAF for each student using the pooled position HSC Student Intern (0 FTE and 0 salary).
  2. Please note: The Department is responsible for processing the full stipend amount of $2,240.  The Department account will be used for half ($1,120) and the Dean’s account for the remaining amount ($1,120).  The FOP can be obtained from Shalene Vick at 743-1830.
  3. Process EOPs prior to June 18th for the first month and July 18th for the second month.
  4. Process ePAF to end job for each student.

Expectations

The research activities of this program are expected to provide meaningful experience and knowledge that contribute to the student’s medical education. Faculty members should offer appropriate instruction and assistance in order for the student to be successful. Students are required to complete a presentation of their research activities during the Student Research Week in the spring 2015. The Office of the Clinical Research Center is providing an opportunity for students to gain better knowledge of the development of protocols for clinical research by attending scheduled lectures early this summer. This will assist the student in understanding the searching of literature, roles and responsibilities of the research team and governing regulations, protection of subjects (consents), data collection (from charts), role of the IRB (risks & benefits), study monitoring and dealing with audits. Additional presentations will be offered throughout the summer on developing a hypothesis, how to give a presentation and writing an abstract. Research seminars presented by TTUHSC faculty members and graduate students will also be presented.

Questions

Any questions regarding this program can be referred to Ernestine Gregorcyk in the Office of the Dean at 743-3003.

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