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Profile for W. LaJean Chaffin, PhD

W. LaJean Chaffin

W. LaJean Chaffin, PhD

  • Professor Emerita
Office Phone: 806-743-2513
Mail Address: 3601 4th St Stop 6591
Lubbock TX 79430-6591


W. LaJean Chaffin, Ph.D., is a Professor in the Department of Immunology and Molecular Microbiology at Texas Tech University Health Sciences Center, Lubbock. Texas. Dr. Chaffin graduated from The University of Texas at Austin in 1964 with a B.A. degree in Chemistry. She graduated Cum Laude and was elected to Phi Beta Kappa. As a graduate student, she trained under Dr. Robert Bock in the area of eycaryotic protein translation working primarily with the model yeast Saccharomyces cerevisiae. She received her Ph.D. in Biochemistry from the University of Wisconsin, Madison in 1972. Dr. Chaffin worked as a Postdoctoral Research Fellow under Dr. Harlyn O. Halvorson, the Director of the Rosenstiel Basic Medical Sciences Research Center at Brandeis University, Waltham, Massachusetts. She was the recipient of National Institutes of Health Postdoctoral Research Fellowship (1975-1976). During this time she continued to work with S. cerevisiae as well as beginning work with Candida albicans. She joined the faculty of Texas Christian University, Ft. Worth, Texas, as an Assistant Professor of Biology (1973-1975. 1976-1980). She spent one year as a Visiting Assistant Professor of Chemistry at Texas Tech University, Lubbock, Texas before joining the Department of Microbiology of the School of Medicine at Texas Tech University Health Sciences Center, Lubbock, Texas in 1981. She received promotion and tenure as an Associate Professor in 1992 and promotion to Professor in 1997. She served as the Interim Chair of the Department of Microbiology and Immunology 1998-2001. She subsequently served as Associate Vice-President for Research and Acting Associate Dean for Research and The Graduate School 2002-2003. She has served on several institutional committees including the Graduate Council for the Graduate School of Biomedical Sciences (1989-1998, 2008-present) and served as its Secretary, 1990-1992 and Chair 1992/1993 and 1994/1995. She currently is a member of the Core Curriculum and Course Evaluation Committees. For the School of Medicine she has served on several committee including the Admissions Committee 1985-2001, Grading and Promotions Committee (chair 1993/1994), Tenure and Promotions (member 2001-2009 and Chair 2006-2007). Dr. Chaffin has served on the Editorial Board of Infection and Immunity and is currently a member of the Editorial Board of Antimicrobial Agents and Chemotherapy and currently is an ad hoc reviewer for several journals. She served as permanent member of NIH AIDS-associated Opportunistic infections and Cancer Study Section as well current various ad hoc assignments. Dr. Chaffin is a member of the Genetics Society of America, Medical Mycological Society of the Americas, International Society for Human and Animal Mycology and the American Society of Microbiology. She was Chair-elect (1995-1996) and Chair (1996-1997) of Division F of the ASM. Dr. Chaffin was a co-organizer of the 1st ASM Conference on Candida and Candidiasis in 1987 and served as member of the Organizing Committee, Chair or co-Chair for for the 2nd and 7th Conferences. Dr. Chaffin’s research has been supported by awards from the North Atlantic Treaty Organization and the National Institutes of Health.

Research Interests

Candida ablicans, candidal biofilms, Candidal cell wall, maintaning commensal populations, chronololgical aging

Teaching Interests

Medical mycology, responsible conduct of research

Selected Publications:

  • Vialás, Vital & Perumal, Palani & Gutierrez, Dolores & Ximénez-Embún, Pilar & Nombela, César & Gil, Concha & Chaffin, W LaJean August (2012) Cell surface shaving of Candida albicans biofilms, hyphae, and yeast form cells. Proteomics, 12, 14, 2331-9.
  • Vialas, Vital & Perumal, Palani & Guiteirrez, Dolores & Ximenez-Emun, Pilar & Nombela, Cesar & Gil, Concha & Chaffin, W August (2012) Cell surface shaving of Candida albicans biofilfims, hyphae and yeast form cells Proteomics, 12, 4, 2331-2339.
  • Martinez-Gomariz, Montserrat & Perumal, Palanie & Mekala, satish & Nombela, Cesar & Chaffin, W & Gil, Concha April (2009) Proteomic analysis of cytoplasmic and surface proteins from yeast cells, hyphae, and biofilms of Candida albicans Proteomics, 9, 6, 2230-2252.
  • Martínez-Gomariz, Montserrat & Perumal, Palani & Mekala, Satish & Nombela, César & Chaffin, W LaJean & Gil, Concha April (2009) Proteomic analysis of cytoplasmic and surface proteins from yeast cells, hyphae, and biofilms of Candida albicans. Proteomics, 9, 8, 2230-52.
  • Chaffin, W September (2008) Candida albicans cell wall proteins Microbiology and Molecular biology reivews, 72, 3, 495-544.