Confocal Facility Manager:
Dr. Ji, appointed as the Pharmacology Neuroscience Department Confocal Facility Manager.
Dr. Guangchen Ji's current research program focuses on the interactions between the
amygdala and cortical areas related to pain. Dr. Ji uses electrophysiological single-cell
recordings in different brain areas and various behavioral assays to correlate neuronal
activity with behavior. For example, computerized vocalization analysis allows the
study of nocifensive and affective components of pain. The elevated plus-maze test
allows the analysis of anxiety-like behavior. Conditioned place-preference assay measures
higher-integrated learning and extinction behavior. A reward-based decision-making
task measures cognitive functions.
Dr. Ji's previous work involved the analysis of peripheral neuroplasticity in chronic
pain. Electrophysiological single fiber recordings in an in vitro skin-nerve preparation
and behavioral assays were used to study pharmacological receptors on peripheral nociceptors
and pain behaviors.
Dr. Ji, appointed as the Pharmacology Neuroscience Department Confocal Facility Manager.
NINDS/NIH, R01 NS109255 - “Pronociceptive and antinociceptive opioid mechanisms in the central nucleus of the
Amygdala”
MPI, Guangchen Ji