Michaela Jansen, PharmD, Ph.D.
Associate Professor of Cell Physiology and Molecular Biophysics
Affiliate Faculty - Biotechnology
Associate Faculty - Pharmacology and Neuroscience
Center for Membrane Protein Research
Texas Tech University Health Sciences Center
3601 4th Street, STOP 6551
Lubbock, Texas 79430
Phone: (806) 743-4059
FAX: (806) 743-1512
Research in the Jansen laboratory focuses on structure and function studies of diverse membrane proteins, specifically, ligand-gated ion channels and transporters. The major focus are neurotransmitter receptors. Our research thus directly relates to neuroscience and also pharmacology.
We apply techniques out of the areas of molecular biology (genetic engineering), biochemistry, chemical biology, and biophysics (electrophysiology, spectroscopy, X-ray crystallography) to study these proteins at a molecular level. We are especially interested in the superfamily of pentameric ligand-gated ion channels (pLGIC) that includes the nACh, GABA, 5HT3, and Gly families. The pLGICs function mainly as neurotransmitter receptors, transforming the chemical signal contained in the neurotransmitter into an electrical signal.
Current and past funding fromt he following sources is gratefully acknowledged:
CMPR at TTUHSC
CTNT at TTUHSC
Office of Research at TTUHSC
We're here to help. Contact us if you have questions.
(806) 743 - 4059