I am primarily interested in molecular mechanisms of activation and regulation of G-protein coupled receptors. I have focused on the receptor for the potent hormone; angiotensin II as a model for the subfamily of G-protein coupled receptors, which bind peptide ligands. Angiotensin II is the effector of the renin-angiotensin system, which plays a critical role in blood pressure regulation and electrolyte balance and which has been implicated in many important medical disorders, including hypertension and diabetes with its associated cardiovascular and renal damage. Consequently, investigating the biochemical and molecular mechanisms of Angiotensin II receptor activation and regulation is crucial for understanding the physiology and pathophysiology of the renin-angiotensin system.
Teaching college students especially in a professional school is both challenging and rewarding. I feel that students need to develop skills for efficient assimilation and interpretation of information. Therefore, they need to know how to think for themselves. I consider it my responsibility to help students learn how to think critically. My expertise is well suited for teaching courses on molecular and cellular biology underlying physiological and pathophysiological processes. Since coming to Texas Tech, my teaching responsibilities here at the School of Pharmacy involve both professional and graduate students. I am an instructional member on several didactic courses including, Pharmacotherapy-Cardiovascular, Principles of Diseases, Case Studies I Tutorial and Pharmaceutical Sciences Cancer Biology, Advanced Principles of Disease, and Research Design and Analysis.