RIO Announcements | Texas Tech University Health Sciences Center
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Cayuse Human Ethics Platform (for IRB Submissions)

We are STILL in the middle of transitioning from iRIS to Cayuse, so please stay tuned for updates and information on training for the Cayuse HE module.  Keep checking this page for updates.

****STUDIES & LEGACY SUBMISSIONS****  Update 08.31.2023


Cayuse Studies VS. Legacy Submissions

The studies that were pulled over from iRIS into Cayuse are essentially empty labeled folders. They do not contain your application, protocol, consent documents, datasheets, etc.

Before you can submit an amendment to your study, a legacy form will have to be completed with all of your currently approved study documentation attached (i.e., protocol, datasheets, consents, etc.).

If you are not sure how to search and start a submission, please review the Cayuse Training here

Please email us at if you have questions.

Thank you for your patience on this matter.




Cayuse is now open for New Exempt study submissions. 

Please review the Cayuse Training here for questions about submitting your Exempt project. We will accept new studies for all others beginning Friday, September 1st, 2023.

If you wish to do so, you can begin submitting your legacy forms for IRB-approved projects from iRIS. Simply search for your study, open it, select "New Submission," and then "Legacy." This process requires your currently approved documents for completion. Those that are not completed by research personnel will be completed by IRB staff by priority and as time allows. 

NOTE: A Legacy Submission Form is required before you can start submitting modifications (i.e., personnel revisions, amendments, etc.). 

If you have any questions, please email us at or call us at:
Amarillo 806-414-9935
Lubbock 806-743-3600


*** Attention Researchers and Research Staff ***

Due to unforeseen problems with data upload into the Cayuse system, the TTUHSC IRBs are extending access to the iRIS system on a temporary basis and until further notice.  

EFFECTIVE IMMEDIATELY - researchers may submit only the following items into the iRIS system during the month of August:
  • Continuing review reports for studies that are due to expire in August
  • Study modifications/amendments of an urgent nature
  • Unanticipated events that are classified as Serious Adverse Events or Unanticipated Problems

* Please note that the Amarillo or Lubbock IRB will NOT be accepting new study applications into the iRIS system during this time.

Additional updates will be sent as soon as the issue with the Cayuse system is resolved.  In the meantime, know that iRIS will remain active.  Please contact your local IRB administrator if you have questions or concerns.

Thank you for your cooperation, and we apologize for any inconvenience this may cause.


For a demo of the HE platform, click HERE.

Notifications sent out re: implementation of HE module:
For additional information, please contact us at



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