Guidelines and Requirements for GSBS Ph.D. Students | Texas Tech University Health Sciences Center

Biomedical Sciences Ph.D. Program 

General Information

The Doctor of Philosophy (Ph.D.) in Biomedical Sciences program is offered on the Lubbock campus only. All students enter this degree program with an undeclared concentration. Students complete the core curriculum and rotate in faculty labs prior to selecting a specific concentration and research mentor. The Biomedical Sciences Ph.D. program offers four concentrations: Biochemistry, Cellular and Molecular Biology; Immunology and Infectious Disease; Molecular Biophysics; Translational Neuroscience and Pharmacology. Specific employment opportunities for graduates include faculty and research positions in academia, biotechnology, pharmaceutical industries, governmental agencies, and governmental appointments.

General Program Requirements

Curriculum

Core Curriculum - Year One, Fall Semester

  • Core I: GSBS 5471 - Molecules
  • Core II: GSBS 5372 - Cells
  • Core III: GSBS 5373 - Genes
  • Core IV: GSBS 5174 - Biomedical Seminar Series
  • Core V: GSBS 5275 - Introduction to Biomedical Research

Responsible Conduct of Research

  • GSBS 5101 - Responsible Conduct of Research
  • Offered during spring semesters only.

Statistics

  • GSBS 5210 - Biomedical Statistics
  • Offered during spring semesters only.

Interprofessional Practice and Education (IPE)

  • Institutional Requirement
  • GSBS 5000 - Interprofessional Collaborative Practice (Year 1, Fall Semester)
  • IPE Learning Activity: Must be completed prior to degree completion.

Lab Rotations - Year 1, Spring and Summer Semesters

  • GSBS 5098 -Techniques in Biomedical Research
  • All students are required to complete three lab rotations prior to declaring a concentration and choosing a lab.

Minimum Required Hours (72)

  • Didactic coursework: 48 credit hours
  • Research coursework: 12 credit hours
  • Dissertation coursework: 12 credit hours

Dissertation

A doctoral dissertation is required of every candidate for a doctoral degree. The doctoral dissertation defense is open to the public and presented as a seminar, followed by a closed-door oral defense with the advisory committee. The dissertation must demonstrate a mastery of research techniques, a thorough understanding of the subject matter and its background, and a high degree of skill in organizing and presenting the materials. The dissertation is presented in a scholarly manuscript and should embody a significant contribution of new information to a subject or a substantial reevaluation of existing knowledge. The dissertation work is continually under the supervision of the advisory committee and any other faculty members the committee or the GSBS office deems necessary.

For detailed information on dissertations, please see the GSBS catalog.

Filing a Degree Plan

Each student must establish a formal degree plan via DegreeWorks in collaboration with the advisory committee during the Spring semester of their second year.

First Authored Paper

Every doctoral student is required to publish an original peer-reviewed research paper to demonstrate that the student has made a significant contribution to science based on work accomplished during their doctoral program.

  • Review articles are not an acceptable contribution
  • The manuscript must be accepted (or accepted pending minor revisions), in press or published before submission of the Approval to Schedule Defense Form.
  • The manuscript must be in a journal indexed by PubMed or Web of Science.
  • The student must be the “first author” or share “first authorship” with a co-author of the manuscript.
  • The work must be completed during the current degree program. Manuscripts published during a previous degree program will not fulfil this requirement.

Waiver to Schedule Defense

If there are compelling reasons that the student will not have a published first-authored manuscript when the approval to schedule defense form is submitted, the dissertation committee chair may request a waiver from the GSBS Dean. The GSBS Dean may grant a waiver based on the information above. The manuscript must be accepted or in press in order for the defense to take place. In considering the waiver request, there are three stipulations:

  1. The student’s mentor and advisory committee must consider the manuscript draft suitable for a first-author (or co-first-author) publication.
  2. The reasons for the delay must be explained
  3. The waiver only allows the student to schedule the defense.

Full-Time Study

Graduate students are required to be enrolled in full-time study throughout their degree program. Please see the GSBS Course Catalog for full details.

Graduate Advisor, Advisory Committee, and Student Progress Assessment

The concentration Graduate Advisor, Student Affairs Advocate, and mentor (if available) will meet with each student at least once a year to monitor the students’ progress and/or address any academic issues.The student will meet with their advisory committee at least twice a year.

  • The student is required to take committee meeting minutes for each meeting.
  • The student will submit a copy of the meeting minutes to the Student Affairs Advocate once the minutes have been approved by the advisory committee.
  • The student will meet with the GSBS Student Affairs Advocate every semester prior to advanced registration and as needed.

Please refer to each concentration’s specific advisory committee member requirements below.

Qualifying Examination

The purpose of the qualifying examination is to ensure that the students have mastered the fundamentals in their major area of interest and are adequately prepared to begin working full-time on a doctoral research project. The examination requires a synthesis and application of knowledge acquired during the course of study for the doctoral degree; consequently, successful performance in coursework does not necessarily guarantee successful performance on the qualifying examination. 

Eligibility

  • Approved degree plan on file with the GSBS office.
  • Completion of core coursework and the majority of additional coursework as prescribed by the approved degree plan.
  • Approval from the advisory committee.

Committee and Chair 

  • The qualifying examination committee will consist of the members of the student’s advisory committee
  • The examination committee will elect an examination chair.
  • The mentor is not eligible to chair the examination committee.

Deadline

  • Students must successfully complete and pass all examination components by the end of their third year.
  • A petition for an extension should be made by the mentor and approved by the GSBS Dean.
  • Failure to meet the deadline and the absence of extenuating circumstances will result in dismissal from the GSBS doctoral degree program.

Admission to Candidacy

  • Authority for admitting an applicant to candidacy for a doctoral degree is vested in the Graduate Council. The advisory committee can submit an admission to candidacy request after the student has successfully completed their qualifying examination to the GSBS office. The request will then be submitted to the Graduate Council for approval.

For detailed information on admission to candidacy, please see the GSBS catalog.

Additional Information

The qualifying examination will consist of two components: written and oral. The qualifying examination topic may be on any relevant research area, but may not be the aims of an existing or submitted research proposal from the mentor or anyone other than the student

Written Component
  • The written portion of the examination will be written in F30/F31 or R21 NIH grant format.
  • The written component must be passed before the oral component can be scheduled
Oral Component
  • The qualifying examination oral component should be presented as a typical public seminar (40-45 minutes) followed by an open Q&A discussion that will not exceed 15 minutes.
  • The presentation will be followed by a closed-door committee examination with the qualifying examination committee.
Examination Voting
  • The qualifying examination committee will vote (pass/fail) on both the written and oral components
  • More than one negative vote for an examination component will result in failure of the examination component.
  • Each exam component (written and oral) can be remediated once.
  • Failure to pass all exam components will result in dismissal from their degree program, or they may be eligible to graduate with a non-thesis master’s degree if they are in good standing and have met all degree requirements.

Timeline

Concentration Specific Information and Requirements

Undeclared

Students in the Biomedical Sciences Ph.D. program enter as undeclared, complete the core curriculum, and rotate in faculty labs prior to selecting a mentor and concentration. Each student will meet with the First-year Student PhD Advisor before or after new student orientation to discuss the year 1 course selections, lab rotations, GSBS policy for selecting a concentration, and other academic issues.

Biochemistry, Cellular and Molecular Biology (BCMB)

The Biochemistry, Cellular and Molecular Biology concentration prepares students for careers in the fields of biochemistry, cellular, developmental, and molecular biology. Dissertation topics in this concentration vary widely. Examples include regulation of gene expression, development and regeneration of the nervous system, protein amyloidogenesis, and tumor microenvironment in cancer progression.

Immunology and Infectious Diseases (IID)

The Immunology and Infectious Diseases concentration integrates several disciplines, such as immunology, bacterial pathogenesis, virology, and parasitology. Dissertation topics in this concentration vary widely. Examples include microbial pathogenesis, biofilms, multi-drug resistance, and tumor antigen identification.

Molecular Biophysics (MBP)

The Molecular Biophysics concentration is geared towards students who have a primary research interest in studying the structure of membrane proteins and their function in health and disease, as well as utilizing cellular and molecular approaches to study these arears. Dissertation topics in this concentration include ion transport and the role of ligand-and voltage-gated potassium channels in normal physiological and pathophysiological conditions, structure/function correlations and structural modeling of ion channels and transporters, and structure-function studies of proteins involved in membrane traffic and fusion.

Translational Neuroscience and Pharmacology (TNP)

The Translational Neuroscience and Pharmacology concentration facilitates graduate study in several areas, including systems and cellular neuropharmacology and neuroscience, molecular pharmacology, biochemistry, and neurobiology of disease. Dissertation topics in this concentration vary widely. Examples include pain mechanisms and therapies in various preclinical models (arthritis, multiple sclerosis, HIV, chemotherapy, and nerve injury-induced neuropathic pain), alcohol abuse disorders, neurodegenerative disorders (Alzheimer’s disease), and anti-neoplastic drug development and mechanisms of drug resistance.