Clinical Research Institute | Texas Tech University Health Sciences Center
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Clinical Research Institute Mission Statement

The mission of the CRI is to promote and facilitate the conduct of clinical research for faculty and trainees while upholding the highest standards of excellence by assuring human subject investigation be performed ethically, responsibly, and professionally to contribute to the health sciences’ body of knowledge.

Patient-Oriented Research

One of the driving factors of the TTUHSC Clinical Research Institute is promoting patient-orientated research. Our office is experienced in conducting Phase I through Phase IV pharmaceutical and device, industry-sponsored, as well as investigator-initiated research protocols. 

Want to help in the advancement of science? Learn how you can make a difference by volunteering in a clinical research study. VOLUNTEER

Education and Training

Conducting research requires knowledge and understanding of the process and the federal regulations involved. The CRI offers a variety of educational programs at multiple experience levels. Some are formally approved courses and electives; others award certificates, however, most include practical application of learned skills. MORE

Services of the Clinical Research Institute

  • Study design: based on statistical considerations from the beginning
  • Data analysis: by a biostatistics/epidemiology group
  • IRB submissions: IRB submission preparation for human study approval
  • Study conduct for in-patient and out-patient projects: recruiting subjects, scheduling appointments, performing procedures (i.e., blood draws), BMD tests, EKGs, etc. and collecting data
  • Dissemination of results

Proposal Review Standards

  • Feasible: adequate subjects and expertise, affordable in terms of time, money and manageable in scope
  • Novel: confirms, refutes or extends previous findings
  • Ethical: acceptable and confidential treatment of subjects
  • Relevant: related to advancing scientific knowledge, clinical and health policy or future research 

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) trial

The Texas Tech University Health Sciences Center is conducting a research study that will look at whether calcium, vasopressin, or both early in the course of treatment would help severely injured patients that lose a lot of blood survive their injuries.

The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) trial will include approximately 1,050 people aged 18 to 90. Patients who have traumatic injuries with loss of blood may be enrolled by participating emergency medical personnel during their transportation to the hospital or after arrival to University Medical Center Hospital.

CAVALIER is an Exception from Informed Consent (EFIC) trial, meaning that, the trial requires performing a potentially life-saving intervention in people who are too injured to give permission. This study will look at treatment for patients who have a traumatic injury and have lost a lot of blood. These patients are too injured to give permission before receiving the study drug. Permission for continued participation will be obtained from patients once they are able, or from their family members, as soon as possible.

For more information about CAVALIER or to complete an anonymous survey on your thoughts about this EFIC study, please go to

This research is supported by DoD contract W81XWH-16-D-0024 W81XWH-22-F-0118. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the Department of the Army, Department of Defense, or the U.S. Government.

• More information on Emergency Research and Exception From Informed Consent (EFIC):