Office of Sciences
The Office of Sciences is available to all faculty on each of the four TTUHSC School of Pharmacy campus sites: Amarillo, Abilene, Dallas/Fort Worth and Lubbock. Our purpose is to act as a resource for the granting process, facilitate research and administer internal research programs.
The Mission of the Office of Sciences at the TTUHSC School of Pharmacy is to coordinate the school's research needs with our state-of-the-art scientific and technical support and to promote and accelerate research grant applications and new award set-up.
June 1-11, 2021 Virtual with zoom
This annual event is a wonderful opportunity for School of Pharmacy's Faculty, Post-Doctoral Research Associates, Graduate students, Residents, and Pharm.D. students to come together from all four campuses to talk about research and build collaborations and friendships. Research Days consists of poster competitions, keynote addresses, podium presentations on current research, breakout sessions, and the annual dinner. MORE
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High Impact Publications
Dr. Hiranmoy Das, Professor in the Pharmaceutical Sciences Department, and his laboratory recently published, "KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism”. To define the regulatory role of Kruppel-like factor 2 (KLF2) during osteoblast (OB) differentiation of dental pulp-derived stem cell (DPSC)s, herein, we show that the levels of KLF2 and autophagy-related molecules were significantly increased in differentiated cells. Gain-of-function and loss-of-function approaches of KLF2 confirmed that KLF2 modulated autophagic and OB differentiation-related molecules. In addition ... (READ ARTICLE) (Impact Factor: 9.986)
Dr. Hiranmoy Das, Professor in the Pharmaceutical Sciences Department, and his laboratory recently published, "KLF2 (kruppel like factor 2 [lung]) regulates osteoclastogenesis by modulating autophagy. "Macroautophagy/autophagy is involved in myeloid cellular repair, destruction, and osteoclast differentiation; conversely, KLF2 (kruppel-like factor 2 [lung]) regulates myeloid cell activation and differentiation. To investigate the specific role of KLF2 in autophagy, osteoclastic differentiation was induced in monocytes in presence or absence of the autophagy inhibitor 3-methyladenine (3-MA), KLF2 inducer...READ ARTICLE
Drs. Magdalena Karbowniczek & Maciej Markiewski, Professors in the Department of Immunotherapeutics and Biotechnology in Abilene, and their team recently published, “Notch transactivates Rheb to maintain the multipotency of TSC-null cells." Differentiation abnormalities are a hallmark of tuberous sclerosis complex (TSC) manifestations; however, the genesis of these abnormalities remains unclear. Here we report on mechanisms controlling the multi-lineage, early neuronal progenitor and neural stem-like cell characteristics of lymphangioleiomyomatosis (LAM) and angiomyolipoma cells. ... READ ARTICLE
This paper was also highlighted by Nature Reviews Nephrology in "Angiomyolipoma: A link between stemness and tumorigenesis in the kidney".