Seminar

*Tuesday, January 31st, 2023, 12:00 p.m.
Distinguished Guest Speaker- Hongmin Wang, Ph.D.
“Targeting proteostasis for neuroprotection in neurodegenerative diseases"

Tuesday, February 14th, 2023, 10 a.m.
Graduate Student- Alejandra Gomez
"The role of the amyloidogenic CRES and CRES subgroup in the brain extracellular matrix: key players in learning and memory?"

*Tuesday, March 7th, 2023, 12 p.m.
Distinguished Guest Speaker- Boris Decourt, Ph.D.
“Developing a Translational Research Program to Test Immunomodulators in Neurodegenerative Disorders: The Example of Lenalidomide”

Dissertation Defense
Tuesday, March 14th, 2023, 10 a.m.
Graduate Student- Valeria Jaramillo-Marinez
"Pharmacoperone approach to treat early infantile epileptic encephalopathy associated with NaCT deficiency"

Tuesday, March 21st, 2023, 12 p.m.
Distinguished Guest Speaker- Guoyan Zhao, Ph.D.
"The molecular mechanisms underpinning selective vulnerability in neurodegenerative diseases"

Dissertation Defense
Wednesday, March 22nd, 2023, 10 a.m.
Graduate Student- Josh Willms
"Novel Tetracycline Reduced Angiogenesis in Mouse Model of Choroidal Neovascularization"

Tuesday, March 28th, 2023, 12 p.m.
Distinguished Guest Speaker- Jenny Wilkerson, Ph.D.
“Cannabis-related compounds and GABA-B receptor agonists as novel therapeutics to treat pathological pain”

Tuesday, April 4th, 2023, 10 a.m.
Graduate Student- Brent Kisby

Tuesday, April 11th, 2023, 10 a.m.
Graduate Student- Praneetha Panthagani
“IND-enabling studies for FDA approval of a modified minocycline analog as an Alcohol Use Disorder medication”

Tuesday, April 25th, 2023, 12 p.m.
Guest Speaker, Tracy Peters, Ph.D.
"Texas Tech University Research Seminar: Project Frontier, Funding and Teaching"

*Wednesday, April 26th, 2023, 10 a.m.
Graduate Student- Xiaobo Liu
"A Novel DSM-V Based Model of Alcohol Use Disorder in Mini Pigs"

Tuesday, May 2nd, 2023, 10 a.m.
M.D./Ph.D. Student- Harry May
“Identification of Differentially Expressed Genes in Neuroblastoma  PDXs in Response to Cyclophosphamide and Topotecan”

Monday, May 8th, 2023, 10 a.m.
Graduate Student- Alejandra Gomez
“CRES as a functional amyloid in the mammalian brain: A potential link to Alzheimer's Disease”

Tuesday, August 16th, 2022, 12:00 p.m.
Distinguished Guest Speaker- I-Chen Ivorine Yu, Ph.D.
“The inflamm-aging axis in microglia and the link to Alzheimer's disease"

*Friday, September 9th, 2022 (12:00 p.m.)
Distinguished Guest Speaker- Yarimar Carrasquillo, Ph.D.
“Circuits and cells for bidirectional control of pain in the amygdala”

*Tuesday, October 4th, 2022, 11 a.m.
Graduate Student- Brent Kisby
“Cell-type Diversity in the Mouse Prefrontal Cortex After Chronic Voluntary  Ethanol Consumption”

Tuesday, October 11th, 2022, 10 a.m.
Graduate Student- Valeria Jaramillo-Martinez
“A three-month internship at a Biotechnology company – a worthwhile experience?”

Tuesday, October 18th, 2022, 10 a.m.
Graduate Student- Xiaobo Liu
“Endothelial Cell Heterogeneity and Microglia Regulons Revealed by a pig cell landscape at single-cell level”

Tuesday, October 25th, 2022, 10 a.m.
Graduate Student- Alejandra Gomez
“CRES and CRES subgroup members as potential functional amyloids in the brain”

Tuesday, November 1st, 2022, 10 a.m.
Graduate Student- Praneetha Panthagani
“Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment”

Tuesday, November 8th, 2022, 12 p.m.
Distinguished Guest Speaker- Sid O'Bryant, Ph.D.
"Examining Alzheimer's Biomarkers Across Diverse Populations in HABS-HD"

Tuesday, December 6th, 2022, 10 a.m.
M.D./Ph.D. Student- Trevor Burrow
"ATM by AZD1390 Enhances Radiotherapy in Pediatric Preclinical Models"

Tuesday, December 13th, 2022 10 a.m.
M.D./Ph.D. Student- Peyton Presto
"Mechanisms of neuroimmune signaling in the amygdala in neuropathic pain."

Tuesday, February 1st, 2022, 10:00 am 
*Distinguished Guest Speaker- Cheryl Stucky, Ph.D.
"More than skin deep: Keratinocytes and somatosensation" 

Tuesday, February 15th, 2022, 10:00 am
Graduate Student- Ryan Sweazy
“A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy"

Wednesday, February 16th, 2022, 12:00 pm
*Distinguished Guest Speaker- Shaolin Liu, Ph.D.
"Understanding Olfactory Function and Dysfunction –from Cellular Networks to Behaviors"

Tuesday, March 1st, 2022, 10:00 am
Alejandra Gomez- Graduate Student
"CRES and CRES subgroup members as potential functional amyloids in the brain"

Qualifying Exam
*Thursday, March 3rd, 2022, 3:00 pm
MD/Ph.D. Student- Trevor Burrow
“Enhancing Radiation Therapy in Alternative Lengthening of Telomeres in Soft Tissue Sarcomas with the ATM inhibitor AZD1390”

Tuesday, March 15th, 2022, 10:00 am
Graduate Student- Xiaobo Liu
“Development of a DSM-V Porcine Model of Alcohol Use Disorder”

Tuesday, March 22nd, 2022, 10:00 am
MD/Ph.D. Student - Josh Willms
“Treatment of inflammatory disorders with modified minocycline analogs"

Dissertation Defense
Thursday, March 31st, 2022, 10:00 am
Graduate Student- Mariacristina Mazzitelli
"Role of amygdala neurons in the modulation of pain with particular focus on CRF neurons"

Tuesday, April 5th 2022, 10:00 am 
Graduate Student - Brent Kisby
"Cell-type specific gene expression changes in the brain in mice leads to excessive alcohol drinking: role of innate immune system"

Tuesday, April 12th, 10:00 am
Graduate Student- Valeria Jaramillo-Martinez
"Function of sodium-coupled citrate transporter NaCT and disfunction in early infantile epileptic encephalopathy"

Tuesday, April 26th, 2022, 10:00 am
Graduate Student- Praneetha Panthagani
"Identifying the epigenetic  role of monoamine neurotransmitters, dopamine and serotonin, in Alcohol Use Disorder"

Tuesday, May 3rd, 2022, 1:00 pm
Distinguished Speaker, Nicholas Gilpin, Ph.D.
"The central amygdala mediates alcohol withdrawal hyperalgesia"

Tuesday, August 24th, 2021, 10:00 am
Graduate Student- Xiaobo Lui
"Development of a DSM-V model of Alcohol Use disorder in miniature swine and evaluation of novel treatment methods"

Tuesday, September 17th, 2021, 12:00 pm 
Distinguished Guest Speaker- Yenisel Cruz-Almeida, MSPH, Ph.D.
"Studying Pain and Aging: A clinical Translational Perspective"

*Qualifying Exam* September 27th, 2021, 1:00 pm
MD/Ph.D Student - Peyton Presto
"Role of neuroimmune signaling in the amygdala in neuropathic pain"

Tuesday, October 19th, 2021, 1:00 pm
Distinguished Guest Speaker- Tamara King-Deeny, Ph.D.
“Impact of sex differences and exercise on osteoarthritis pain”

Wednesday, November 3rd, 2021, 1:00 pm
Distinguished Guest Speaker- Jeannie Chin, Ph.D.
"Circuit and network mechanisms of cognitive deficits in Alzheimer’s disease” 

Tuesday, November 11th, 2021, 10:00 am
MD/Ph.D. Student- Trevor Burrow
“The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models”

Tuesday, November 16th, 2021 
Distinguished Guest Speaker- Marc Tambini, M.D., Ph.D.
“Novel rat knock-in models of Alzheimer's Disease"

Tuesday, November 23rd, 2021, 10:00 am
MD/Ph.D. Student - Josh Willms
"Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes"

Tuesday, November 30th, 2021, 10:00 am
Graduate Student- Mariacristina Mazzitelli
"Differential nervous system functions of mGluR2 and mGluR3"

Tuesday, December 14th, 2021, 12:00 pm
Distinguished Guest Speaker- Tor Wager, PhD
"Chronic pain: From brain circuits to psychological intervention"

June 25th, 2021 10:00 am
Ph.D. Candidate- Henry Blanton
"Sex differences in pain and the endocannabinoid system"

May 11, 2021 10:00 am
Graduate Student - Josh Willms
"Treatment of Inflammatory Disorder with Modified Minocycline Analogs:  Rheumatoid arthritis

May 4, 2021, 10:00 am
Graduate Student - Mariacristina Mazzitelli
"Pharmacological and optogenetic manipulation of amygdala in pain"

April 27, 2021, 10:00 am
Graduate Student - Xiaobo Liu
"Development of a porcine model of a DSM-D"

April 13, 2021, 10:00 am
Graduate Student - Ryan Sweazey
"Mutations in ATP1A1 Cuase Dominant Charcot-Marie-tooth Type 2"

April 6, 2021, 10:00 am
Graduate Student - Trevor Burrow
"The Telomeric DNA C-circle Assay as a Companion Diagnostic for the p53-activating drug APR-246"

April 2, 2021, 11:00 am
Graduate Student (Dissertation Defense) - Ismail S. Mohiuddin
"Narciclasine Impairs c-MYC Activity by Inhibiting DNA-PKcs-Mediated Phosphorylation of OCT4 in Small Cell Lung Cancer"

March 23, 2021, 10:00 am
Graduate Student - Praneetha Panthagani
"Identifying Biomarkers for Alcohol Use Disorder"

March 16, 2021, 10:00 am
Graduate Student - Valeria Jaramillo-Martinez
"Structural insights and classification of the disease-causing mutations in human Na+- coupled citrate transporter (NaCT)"

March 8, 2021, 12:00 pm
Distinguished Guest Speaker - Dr. Laura Ibanez
"Biomarker tools for Alzheimer's Disease using high throughput data"

March 3, 2021, 12:00 pm 
Distinguished Guest Speaker - Dr. Bhaskar Das
"Boron Based Probes and Pharmacological Agents for Brain Diseases"

March 2, 2021, 12:00 pm
Distinguished Guest Speaker - Dr. Holly Hunsberger
"The impact of anxiety on Alzheimer's disease progression: of mice and (Wo)men"

February 2, 2021, 12:00 pm
Distinguished Guest Speaker- Dr. Haining Zhu
"RNA Metabolism and Translational Regulatio in Neurodegenerative Diseases"

January 26, 2021, 12:00 pm
Distinguished Guest Speaker - Dr. Nikhil Panicker
"Innate immune responses to alpha-synuclein facilitate its progressive aggregation"

January 19, 2021, 12:00 pm
Distinguished Guest Speaker - Dr. Pooja Jadiya
"Mitochondrial calcium signaling in Alzheimer's Disease"

December 8, 2020, 10:00 am
Graduate Student- Mariacristina Mazzitelli
"Optogenetic manipulation of amygdala CRF neurons in pain"

December 1, 2020, 10:00 am
Graduate Student- Peyton Presto
"Neuron-microglia interactions in the brain in a neuropathic pain model"

November 17, 2020, 10:00 am
Graduate Student- Xiaobo Liu
"Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain”  

November 10, 2020, 10:00 am
Graduate Student- Ismail Mohiuddin
"Targeting DNA Damage Response Promotes Antitumor Immunity through STINGMediated T-cell Activation in Small Cell Lung Cancer" 

November 9, 2020, 12:00 pm
National Alzheimer's Disease Awareness Month
Distinguished Guest Speaker- Dr. Claudio Soto
"The Prion Principle at the Root of Neurodegenerative Diseases: Implications for Treatment and Diagnosis"    

November 3, 2020, 10:00 am
Graduate Student- Valeria Jaramillo- Martinez
"Molecular Basis for Inhibition of the Na+/Citrate Transporter NaCT (SLC13A5) by Dicarboxylate Inhibitors"    

October 30, 2020, 12:00 PM
Distinguished Guest Speaker - CORE IV Seminar Series
Dr. Thomas Abbruscato
"Nicotine and electronic cigarette (E-Cig) exposure decreases brain glucose utilization in ischemic stroke"     

October 20, 2020, 12:00 pm
Distinguished Guest Speaker- Dr. Andrey Karamyshev
"Defects in Protein Biogenesis and Human Diseases"  

October 6, 2020, 10:00 am
Graduate Student- Henry Blanton
"Sex Differences in Cannabinoid Analgesia"       

September 29, 2020, 10:00 am
Graduate Student- Trevor Burrow
"The C-Circle Assay for alternative-lengthening-of-telomeres activity"     

September 22, 2020, 10:00 am
Graduate Student - Josh Willms
"Minocycline protects developing brain against ethanol-induced damage"