Profile for Constantinos Mikelis, PhD

Constantinos Mikelis

Constantinos Mikelis, PhD

  • Assistant Professor Pharmaceutical Sci Amarillo
Office Phone: 806-414-9242
Mail Address: 1406 S Coulter St, Amarillo Research Building
Amarillo TX 79106



B.S. Biology (2002), University of Patras, Greece.
M.S. Molecular Pharmacology (2004), University of Patras, Greece.
Ph.D. Molecular Pharmacology (2009), University of Patras, Greece.
Sabbatical Training (2009), German Cancer Research Center (dkfz), Heidelberg, Germany.
Postdoc (2009-2014), Oral and Pharyngeal Cancer Branch, NIDCR, NIH, Bethesda, MD.

Research Interests

Vascular biology, angiogenesis, tumor metastasis.

Teaching Interests

PharmD Courses: Principles of Disease (PHAR1221), Clinical Research and Literature Evaluation (PHAR1241), Case studies I (PHAR3361).

Graduate Courses: Experimental Design and Biostatistics (GPSC5230), Advanced Principles of Disease (GPSC5356), Cancer Biology and Therapeutics (GPSC5326).

Selected Publications:

  • Sajib S, Zahra FT, Lionakis MS, German N, Mikelis C. Mechanisms of angiogenesis in microbe-regulated inflammatory and neoplastic conditions.. Angiogenesis 2017.
  • Ranjan A, German N, Mikelis C, Srivenugopal KS, Srivastava SK. Penfluridol induces endoplasmic reticulum stress leading to autophagy in pancreatic cancer.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017;39(6):1010428317705517.
  • Doçi CL, Mikelis C, Callejas-Valera JL, Hansen KK, Molinolo AA, Inoue A, Offermanns S, Gutkind JS. Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.. PloS one 2017;12(3):e0173692.
  • Rieber N, Gazendam RP, Freeman AF, Hsu AP, Collar AL, Sugui JA, Drummond RA, Rongkavilit C, Hoffman K, Henderson C, Clark L, Mezger M, Swamydas M, Engeholm M, Schüle R, Neumayer B, Ebel F, Mikelis C, Pittaluga S, Prasad VK, Singh A, Milner JD, Williams KW, Lim JK, Kwon-Chung KJ, Holland SM, Hartl D, Kuijpers TW, Lionakis MS. Extrapulmonary Aspergillus infection in patients with CARD9 deficiency.. JCI insight 2016;1(17):e89890.
  • Doçi CL, Mikelis C, Lionakis MS, Molinolo AA, Gutkind JS. Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma.. Cancer research 2015.