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Second Galveston Symposium on Alzheimer's Disease and Related Disorders: Basic, Translational and Clinical Updates

Garrison Institute on Aging faculty attended the Second Galveston Symposium on Alzheimer's Disease and Related Disorders Conference. GIA Faculty had the opportunity to meet new potential collaborators and present their findings. Dr. John Josh Lawrence presented his recent findings. See details below.

Protection of Inhibitory Circuit Dysfunction During Alzheimer’s Disease Pathogenesis through Preservation of Retinoic Acid Signaling 

Authors:  Anthony J. Pascullo,  Rui Wang, Jeremy Bailoo, Fowzia Selina, Toby Anderson, Xiaobo Liu, Robert Barnes, and J. Josh Lawrence
 
In the hippocampus, a balance between excitatory and inhibitory circuits is critical for normal learning and memory operations.   In Alzheimer’s disease (AD), amyloid precursor protein is metabolized into amyloid beta (Ab), which form Ab plaques that ultimately cause premature death.  In the earliest stages of AD, performance during learning tasks is impaired, which is accompanied by hyperexcitability within the dentate gyrus (DG) and CA3 regions of the hippocampus. For a complete review of Dr. Lawrence's abstract click here.

2019 Research Retreat

The Department of Pharmacology and Neuroscience and Garrison Institute on Aging Annual Research Retreat will be held October 3-5 in Austin, Texas.

Keynote Speaker:  R. Adron Harris, PhD | Associate Director, The University of Texas at Austin Waggoner Center for Alcohol and Addiction Research | Professor of Neuroscience, Psychiatry and Pharmacology | M. June and J. Virgil Waggoner Chair in Molecular Biology

 

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